Advances in the effects of intestinal flora imbalance on ischemic stroke and in traditional Chinese medicine management

Liang Wei; Meizhen Zhu; Shijie Sun; Rui Yu; Xianjing Zeng

doi:10.3969/j.issn.2095-6606.2021.05.017

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Advances in the effects of intestinal flora imbalance on ischemic stroke and in traditional Chinese medicine management

更新时间：2021-10-19

- Advances in the effects of intestinal flora imbalance on ischemic stroke and in traditional Chinese medicine management
- Modern Chinese Clinical Medicine Vol. 28, Issue 5, Pages: 72-76(2021)
- 作者机构：
  
  广西中医药大学　广西　 530001
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2021.05.017
  CLC： R259
- Published：30 September 2021，
  
  Received：23 September 2020，
- 稿件说明：
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Liang Wei, Meizhen Zhu, Shijie Sun, et al. Advances in the effects of intestinal flora imbalance on ischemic stroke and in traditional Chinese medicine management. [J]. Modern Chinese Clinical Medicine 28(5):72-76(2021)
DOI：

Liang Wei, Meizhen Zhu, Shijie Sun, et al. Advances in the effects of intestinal flora imbalance on ischemic stroke and in traditional Chinese medicine management. [J]. Modern Chinese Clinical Medicine 28(5):72-76(2021) DOI： 10.3969/j.issn.2095-6606.2021.05.017.

摘要

近年来，从肠到脑的信号通路作为缺血性脑卒中不可忽视的影响因素而备受关注，肠道菌群参与缺血性脑卒中高危致病因素的生成。中医认为脑与肠腑在生理上通过经络密切联系，功能上相互滋养、相互调节；在病理上，脑病可及肠腑，肠病可及脑腑，二者相互影响。基于此可将调控肠道菌群趋于稳定作为研究缺血性脑卒中治疗方法的切入点，目前，包括中药活性成分、中药单体、中药复方以及针灸等在内的中医药治疗方法，通过调控肠道菌群改善缺血性脑卒中的发生、发展及预后已取得一定进展，本文对中医药基于肠道菌群防治缺血性脑卒中进行综述。

Abstract

In recent years

the signaling pathway from the intestine to the brain has attracted much attention as a non-negligible influencing factor in ischemic stroke. Intestinal flora is involved in the generation of high-risk pathogenic factors in ischemic stroke. Traditional Chinese medicine believes that the brain and intestines are closely connected physiologically through the meridians

and functionally they nourish and regulate each other; pathologically

encephalopathy may affect the intestines

and intestinal diseases may affect the brain

and the two influence each other. Based on this understanding

the regulation of intestinal flora stabilization can be used as an entry point to study the treatment of ischemic stroke. At present

the treatment methods of traditional Chinese medicine including the active ingredients of traditional Chinese medicine

the monomer of traditional Chinese medicine

the compounds of traditional Chinese medicine and acupuncture are adopted. Some progress has been made in regulating the intestinal flora to improve the occurrence

development and prognosis of ischemic stroke. This article reviews the prevention and treatment of ischemic stroke based on intestinal flora in traditional Chinese medicine.

关键词

中医药肠道菌群缺血性脑卒中综述

Keywords

traditional Chinese medicineintestinal floraischemic strokereview

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