Therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in children

Meijuan Chen; Wen Zhang; Wenying Gao

doi:10.3969/j.issn.2095-6606.2021.06.005

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Therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in children

更新时间：2021-12-06

- Therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in children
- Modern Chinese Clinical Medicine Vol. 28, Issue 6, Pages: 24-27(2021)
- 作者机构：
  
  1.江门市妇幼保健院儿科　广东　529000
  2.北京中医药大学第三附属医院儿科
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2021.06.005
  CLC： R272.6
- Published：30 November 2021，
  
  Received：10 February 2021，
- 稿件说明：
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Meijuan Chen, Wen Zhang, Wenying Gao. Therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in children. [J]. Modern Chinese Clinical Medicine 28(6):24-27(2021)
DOI：

Meijuan Chen, Wen Zhang, Wenying Gao. Therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in children. [J]. Modern Chinese Clinical Medicine 28(6):24-27(2021) DOI： 10.3969/j.issn.2095-6606.2021.06.005.

摘要

目的

观察滋阴降火法治疗女童中枢性性早熟的疗效。

方法

对42例女童特发性中枢性性早熟患儿予滋阴降火中药口服，记录治疗前后的中医证候、子宫、卵巢、促性腺激素及性激素

即黄体生成素（LH），促卵泡激素（FSH），雌二醇（E2）和骨龄的变化。

结果

与治疗前比较，治疗后患儿的各项临床症状积分均改善，差异具有统计学意义（

0.05）；治疗后患儿子宫、卵巢容积大小均减小，差异具有统计学意义（

0.05）；治疗后患儿血清LH，FSH，E2均较治疗前下降，差异具有统计学意义（

0.05）；患儿治疗后（BA/CA）小于治疗前（BA/CA），差异具有统计学意义（

0.05）。

结论

滋阴降火中药对防治女童特发性中枢性性早熟有临床疗效，能改善患儿临床症状。

Abstract

Objective

To observe curative effect of the Chinese medical therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in girls.

Methods

Forty-two girls with true idiopathic central precocious puberty were treated with Chinese medical therapy of nourishing yin and downbearing fire.The changes in TCM symptoms

size of the uterus and ovary

gonadotropins

sexhormones

i.e.

luteinizing hormone(LH)

follicle-stimulating hormone (FSH)

estradiol(E2)

X-ray bone age before and after the treatment were recorded.

Results

After treatment

the scores of clinical symptoms were significantly decreased

as compared with those before treatment (

0.05); After treatment

serum LH

FSH and E2 levels were significantly lowered(

0.05); The size of uterus and ovary was significantly decreased

as compared with those before treatment(

0.05); After treatment

the bone age/chronological age values were significantly reduced (

0.05).

Conclusions

The Chinese medical therapy of nourishing yin and downbearing fire

which relieves clinical symptoms

is of efficacy for children with idiopathic central precocious puberty.

关键词

特发性性早熟滋阴降火中医药

Keywords

idiopathic central precocious puberty(ICPP)nourishing yin and downbearing firetraditional Chinese medicine

references

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