Acupuncture treatment ideas for ischemic stroke by regulating intestinal function following "intestinal injuries affecting the brain" after ischemicstroke

Yini Hua; Jinhong Liu; Xiaona Wu; Jingni Xu; Haoyue Yan; Jinxia Ni

doi:10.3969/j.issn.2095-6606.2021.06.011

您当前的位置：

首页 >

文章列表页 >

Acupuncture treatment ideas for ischemic stroke by regulating intestinal function following "intestinal injuries affecting the brain" after ischemicstroke

更新时间：2021-12-06

- Acupuncture treatment ideas for ischemic stroke by regulating intestinal function following "intestinal injuries affecting the brain" after ischemicstroke
- Modern Chinese Clinical Medicine Vol. 28, Issue 6, Pages: 53-57(2021)
- 作者机构：
  
  北京中医药大学东直门医院　北京 100700
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2021.06.011
  CLC： R255.2
- Published：30 November 2021，
  
  Received：25 May 2021，
- 稿件说明：
移动端阅览
Yini Hua, Jinhong Liu, Xiaona Wu, et al. Acupuncture treatment ideas for ischemic stroke by regulating intestinal function following "intestinal injuries affecting the brain" after ischemicstroke. [J]. Modern Chinese Clinical Medicine 28(6):53-57(2021)
DOI：

Yini Hua, Jinhong Liu, Xiaona Wu, et al. Acupuncture treatment ideas for ischemic stroke by regulating intestinal function following "intestinal injuries affecting the brain" after ischemicstroke. [J]. Modern Chinese Clinical Medicine 28(6):53-57(2021) DOI： 10.3969/j.issn.2095-6606.2021.06.011.

摘要

缺血性脑卒中发作后，脑部损伤会影响肠道功能，而肠道功能失常又会进一步加重脑部损伤，形成病理上互相干扰的恶性循环。中医两千年前即有脑肠相关的医学论述，现代脑肠轴理论又证实胃肠道与脑之间存在涉及神经、内分泌、免疫等多方面联系的双向调节系统，本文旨在从肠腑的角度出发，分别从津液代谢、气机升降、神明调控、经脉荣通等方面阐述肠腑功能失用加重脑损的中医机理，探讨在这种双向互相影响下“肠损及脑”对针灸治疗缺血性脑卒中从肠论治的指导思路。

Abstract

After an ischemic stroke

brain injuries will affect intestinal function

and intestinal dysfunction will further aggravate brain injuries

forming a pathologically interfering vicious circle.Two thousand years ago

there were medical discourses related to the brain-gut in traditional Chinese medicine. The modern brain-gut axis theory has confirmed that there is a two-way regulatory system between the gastrointestinal tract and the brain that involves nerves

endocrine

immunity and other aspects.From the perspective of viscera and bowels

this article explainsthe mechanism of intestinal dysfunction aggravating brain injuries in terms of body fluid metabolism

lifting and lowering movements of qi

Shenmingregulation

meridian rongtong

etc.

and explores the effect of "intestinal injuriesaffecting the brain" by acupuncture treatment under this two-way mutual influence.

关键词

缺血性脑卒中肠损及脑针刺从肠论治

Keywords

ischemic strokeintestinal injuries affecting the brainacupunctureregulating intestinal function

references

郭椿,贺平.脑肠轴及其研究进展[J].世界最新医学信息文摘,2017,17(95):89-91.

王永炎,张伯礼.中医脑病学[M].北京:人民卫生出版社,2007:137.

陈斌.缺血性脑卒中二级预防研究进展[J].中国实用医药,2019,14(22):194-195.

孙双喜,白小欣.从中医生理病理角度谈对脑肠轴的认识[J].陕西中医,2017,38(6):787-788.

游超,曾秀丽,高徐璇,等.脑梗死患者肠道菌群紊乱与恢复研究[J].中国神经精神疾病杂志,2018,44(3):149-154.

倪光夏,宋扬扬.基于“脑肠轴”理论探讨“醒神调肠”针刺法治疗帕金森病[J].中国针灸,2020,40(3):315-317.

刘小雄.大柴胡汤治疗证属少阳阳明经合病缺血性卒中急性期的临床疗效观察[D].南宁：广西中医药大学,2017.

MORTON CAROLINE E,FORBES HARRIET J,PEARCEN ,et al. Association Between Common Infections and Incident Post-Stroke Dementia: A Cohort Study Using the Clinical Practice Research Datalink[J].Clinical Epidemiology，2020,12:907-916.

徐梦,许奔奔,孟新玲.肠道菌群与血管性痴呆的相关性研究[J].世界最新医学信息文摘,2019,19(92):121-122.

刘巨海.基于中医古代文献的小肠藏象理论研究[D].济南：山东中医药大学,2014.

卢殿强,孙志广.基于脑肠轴探讨“心脾相关”在临床中的应用[J].河北中医,2019,41(8):1257-1260.

郭宗耀,刘芸,高玉萍,等.“心与小肠相表里”理论的源流与发展[J].中医杂志,2017,58(2):96-99.

尹涛,孙睿睿,何昭璇,等.略论“大肠小肠皆属于胃”[J].湖南中医杂志,2016,32(11):138-140.

聂玉婷,高利.基于肠道菌群失调探讨脑系疾病从脾胃论治[J].中国中西医结合杂志2019,39(11):1390-1394.

赵吉平,李瑛,等.针灸学[M].北京:人民卫生出版社,2016:255-258.

李琳靖,高利.脑中风与胃肠道的关系[J].中西医结合心脑血管病杂志,2018,16(15):2162-2164.

YIN J,LIAO S X,HEY ,et al. Dysbiosis of gut microbiota with reducedtrimethylamine-N-oxide level in patients with large-artery atheroscle-rotic stroke or transient ischemic attack[J].Journal of the AmericanHeart Association,2015,4(11):e2699.

SINGH V,ROTH S,LLOVERA G,et al.Microbiota Dysbiosis Controls theNeuroinflammatory Response after Stroke[J].The Journal of neuroscience: the official journal of the society for neuroscie，2016,36(28):7428-7440.

CHEN Y H, LIANG J H, QUYANG F B, et al. Persistence of gut microbiota dysbiosis and chronic systemic inflammation after cerebral infarction in cynomolgus monkeys[J].Frontiersin neurology,2019,10:661

CHEN R Z, XU Y, WU P, et al. Transplantation of fecal microbiota rich in short chain fatty acids and butyricacid treat cerebral ischemic stroke by regulatinggutmicrobiota[J].Pharmacological research,2019,148:104403.

向俊璐.不同时机针刺治疗缺血性中风病的临床研究[D].长沙：湖北中医药大学,2013.

CEHN P,JIANG L,GENG H L, et al. Effectiveness of XinglouChengqi decoction on constipation in patients with acute ischemic stroke: a randomized controlled trial[J].Journal of Traditionnal Chinese Medicine: Chuang itsachihying wenpan， 2020,40(1):112-120.

马祥雪,王凤云,符竣杰,等.基于肠道菌群的中医健脾方剂作用机制的研究现状与思考[J].中国实验方剂学杂志,2017,23(5):210-215.

刘飞,郭换,梁乙川,等.基于降血脂功效的决明子安全性评价[J].中国实验方剂学杂志,2017,23(17):183-189.

王琳琳.针灸治疗缺血性脑卒中后便秘的疗效观察[J].中国医药指南,2020,18(10):185-186.

周尊奎.足三里穴电针恢复脑卒中患者胃肠功能的临床观察[J].浙江中医药大学学报,2018,42(5):401-403.

李湘力,蔡敬宙,林泳,等.针刺疗法调节IBS-D大鼠肠道菌群结构和促进肠紧密连接的作用研究[J].广州中医药大学学报,2019,36(7):1022-1028.

叶晓倩.基于体素形态学分析针刺干预缺血性脑卒中肢体运动功能障碍的作用机制研究[D].福州：福建中医药大学,2017.

唐永祥,王晓玲,贺君,等.脑卒中后抑郁症“因虚致郁”病机探讨[J].湖南中医杂志,2012,28(3):103-104.

许翊坂.柴芍地黄汤加减治疗中风后抑郁症疗效观察[J].光明中医,2013,28(11):2295-2296.

吉思,马秋平.针灸治疗脑卒中后抑郁中腧穴的应用规律[J].中国老年学杂志,2017,37(16):3988-3989.

范文涛,闫咏梅,别玉龙,等.大鼠卒中后肠道菌群紊乱与抑郁的关系[J].中国脑血管病杂志,2016,13(12):644-649.

周雨慧,芦锰,苗明三.基于肠道菌群的血管性痴呆的中医药防治[J].中药药理与临床,2019,35(5):172-175.

唐圆,谭周进.中医药对肠道微生态的影响[J].世界华人消化杂志,2020,28(15):719-724.

CAMARA-LEMARROY C R,METZ L M,YONG VW. Focus on the gut-brain axis: multiple sclerosis,the intestinal barrier and the microbiome[J].World J Gastroenterol,2018:24(37):4-10.

王燕,石剑,贡丽雅,等.“脑-肠轴”学说研究益生菌联合肠内营养对脑梗死大鼠免疫及认知功能的影响[J].中国老年学杂志,2020,40(15):3288-3292.

彭拥军,徐疏影,吕鹤群,等.针灸与肠道菌群[J/OL].辽宁中医药大学学报:1-11[2020-11-29].http://kns.cnki.net/kcms/detail/21.1543.R.20200720.1714.004.htmlhttp://kns.cnki.net/kcms/detail/21.1543.R.20200720.1714.004.html.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Efficacy and safety of acupuncture in the treatment of tension-type headache: a Meta analysis

Therapeutic mechanism of local acupuncture for secondary lymphedema of limbs based on the theory of "treating where it hurts"

Clinical study of acupuncture in the treatment of hand-foot syndrome

Clinical efficacy of bypass therapy of Yin and Yang Qiaomai in combination with the Gen Liu Zhu Ru for idiopathic facial paralysis

Effect of acupuncture at Shenmen (HT 7) on amplitude of low frequency fluctuation after sleep deprivation based on cortical analysis

Related Author

ZHANG Teng

LU Yonghui

YIN Yue

TU Ya

JIANG Huili

NIU Shaohui

LI Bei

CHENG Yaqing

Related Institution

International Research Center for Mental Disorders, School of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine

Yanjing Medical College, Capital Medical University

Beijing University of Chinese Medicine

Xiyuan Hospital, China Academy of Chinese Medical Sciences

Dongfang Hospital, Beijing University of Chinese Medicine

⁰