Treatment of anorexia in children by Feng’s spine-pinching manipulation: a randomized controlled trial

Sushi WANG; Yan WANG; Ming LI; Muchan LI; Huan YANG; Feng LIU; Dongdi WANG; Ya SU; Yingqi TIAN; Min LI

doi:10.3969/j.issn.2095-6606.2022.03.003

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Treatment of anorexia in children by Feng’s spine-pinching manipulation: a randomized controlled trial

更新时间：2022-06-02

- Treatment of anorexia in children by Feng’s spine-pinching manipulation: a randomized controlled trial
- Modern Chinese Clinical Medicine Vol. 29, Issue 3, Pages: 13-18(2022)
- 作者机构：
  
  1.首都医科大学附属北京中医医院儿科　北京　100010
  2.河北省邯郸市邱县中心医院儿科
  3.首都医科大学附属北京中医医院信息中心
  4.北京市海淀区北太平庄社区卫生服务中心中医科
  5.北京市东城区朝阳门社区卫生服务中心中医科
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2022.03.003
  CLC： R272
- Published：30 May 2022，
  
  Received：12 June 2021，
- 稿件说明：
移动端阅览
Sushi WANG, Yan WANG, Ming LI, et al. Treatment of anorexia in children by Feng’s spine-pinching manipulation: a randomized controlled trial. [J]. Modern Chinese Clinical Medicine 29(3):13-18(2022)
DOI：

Sushi WANG, Yan WANG, Ming LI, et al. Treatment of anorexia in children by Feng’s spine-pinching manipulation: a randomized controlled trial. [J]. Modern Chinese Clinical Medicine 29(3):13-18(2022) DOI： 10.3969/j.issn.2095-6606.2022.03.003.

摘要

目的

通过不同捏脊手法、捏脊部位对厌食症患儿食欲因子影响的随机对照研究，挖掘冯氏捏脊手法特色。

方法

将127例厌食症患儿随机分为3组：冯氏捏脊治疗组(简称冯氏组)46例、三指捏脊治疗组(简称三指组)42例、非捏脊穴位对照组(简称对照组)39例。剔除脱落病例后，冯氏组37例、三指组35例、对照组30例。观察胃饥饿素(Ghrelin)和瘦素(Leptin)水平、症状量表评分、临床疗效、身高、体重、身体质量指数(BMI)，并进行安全性评估。

结果

3组患儿Ghrelin水平比较，三指组和对照组Ghrelin水平较本组治疗前均上升，差异均有统计学意义(

0.05)。3组治疗前后差值比较，差异有统计学意义(

0.05)。与对照组比较，冯氏组Ghrelin水平治疗前后差值较低，差异有统计学意义(

0.05)。3组患儿Leptin水平比较，对照组Leptin水平较本组治疗前下降，差异有统计学意义(

0.05)。3组症状量表评分较本组治疗前均下降，差异均有统计学意义(

0.05)。3组症状量表评分治疗前后差值比较，差异有统计学意义(

0.05)。与对照组比较，冯氏组症状量表评分治疗前后差值较低，差异有统计学意义(

0.05)。与冯氏组比较，三指组症状量表评分治疗前后差值较低，差异有统计学意义(

0.05)。对治疗后各指标进行Spearman秩相关分析，结果显示治疗后患儿的Ghrelin和年龄呈正相关关系(

＝0.248，

＝0.012)。

结论

冯氏捏脊手法善于增强饮食摄入和(或)营养吸收，提高BMI或脂肪含量。

Abstract

Objective

To explore the characteristics of Feng’s spine-pinching manipulation by measuring the effect of different manipulations and positions of pinching on the secretion of ghrelin and leptin

two factors that affect appetite

of children with anorexia.

Methods

102 children were randomly divided into three groups: 46 in the group of Feng’s spine-pinching manipulation (the Feng’s group)

42 in the group of the "three-finger" spine-pinching manipulation (the three-finger group) and 39 in the control group (manipulations conducted at locations that are not the acupoints targeted by the Feng technique). After those who dropped out were removed

there were 37 patients in the Feng’s group

35 in the three-finger group

and 30 in the control group. Their levels of ghrelin and leptin were measured before and after treatment

along with other indicators including symptom scale score

clinical efficacy

height

weight

BMI

and safety assessment.

Results

A comparison of ghrelin levels of children in the three groups reveals that ghrelin levels in both the three-finger and control groups increased compared to their respective pre-treatment levels

and the differences were statistically significant (

0.05). The differences before and after treatment in the three groups were statistically significant (

0.05). Compared with the control group

the difference of ghrelin level in the Feng’s group before and after treatment was lower

and the difference was statistically significant (

0.05). The post-treatment leptin level in the control group decreased compared with that before treatment

and the difference was statistically significant (

0.05). The respective differences in the symptom scale scores in the 3 groups before and after treatment were statistically significant (

0.05). Compared with the control group

the difference between the pre- and post-treatment symptom scale scores was lower in the Feng’s group

and the difference was statistically significant (

0.05). Compared with the Feng’s group

the difference between pre- and post-treatment was lower in the symptom scale scores in the three-finger group

and the difference was statistically significant (

0.05). Spearman’s rank correlation analysis of the post-treatment indicators showed a positive correlation between ghrelin levels and age of the children after treatment (

=0.248

=0.012).

Conclusions

Feng’s spine-pinching manipulation can effectively promote dietary intake and/or digestion to increase the BMI or fat content.

关键词

冯氏捏脊厌食胃饥饿素瘦素身体质量指数随机对照

Keywords

Feng’s spine-pinching manipulationanorexiaghrelinleptinBMIrandomized control

references

汪受传.中医儿科学[M].2版.北京：中国中医药出版社，2007:106-107.

陈志凤.厌食症儿童血Ghrelin、Leptin与NPY的水平变化及其临床意义[D].广州：中山大学，2006.

佘继林.冯氏捏积疗法[M].北京：知识出版社，1985:1-2.

郑筱萸.中药新药临床研究指导原则(试行)[M].北京：中国医药科技出版社，2002:267-269.

中华中医药学会.中医儿科常见病诊疗指南[M].北京：中国中医药出版社，2012:48-51.

王冠军，龚清海，李辉，等.睡眠对儿童血清Leptin、Ghrelin及血脂水平影响的前瞻性研究[J].中国现代医生，2020, 58(15):170-173,185.

MIARA M, MILLER K K, HERZOG D B, et al.Growth hormone and ghrelin responses to an oral glucose load in adolescent girls with anorexia nervosa and controls[J].J Clin Endocrinol Metab，2004, 89(4):1605-1612.

KOYAMA K I, YASUHARA D, NAKAHARA T, et al. Changes in acyl ghrelin, des-acyl ghrelin, and ratio of acyl ghrelin to total ghrelin with short-term refeeding in female inpatients with restricting-type anorexia nervosa[J].Horm Metab Res，2010, 42(8):595-598.

OTTO B, CUNTZ U, WAWARTA R, et al.Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa[J].Eur J Endocrinol，2001, 145(5):669-673.

MISRA M, MILLER K K, KUO K, et al.Secretory dynamics of ghrelin in adolescent girls with anorexia nervosa and healthy adolescents[J].Am J Physiol Endocrinol Metab，2005, 289(2):E347-E356.

SCHORR M, MILLER K K.The endocrine manifestations of anorexia nervosa: mechanisms and management[J].Nat Rev Endocrinol，2017, 13(3):174-186.

IKEZAKI A, HOSODA H, ITO K, et al.Fasting plasma ghrelin levels are negatively correlated with insulin resistance and PAI-1, but not with leptin, in obese children and adolescents[J].Diabetes，2002, 51(12):3408-3411.

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