Novel explanation of Chai Songyan’s academic viewpoint of "<italic style="font-style: italic">yangming</italic> channels pathogenic theory" in the treatment of polycystic ovary syndrome

WANG Yang; TONG Qing; LIN Qing; CHEN Ying; LIU Chunhui

doi:10.3969/j.issn.2095-6606.2022.05.010

您当前的位置：

首页 >

文章列表页 >

Novel explanation of Chai Songyan’s academic viewpoint of "yangming channels pathogenic theory" in the treatment of polycystic ovary syndrome

更新时间：2022-10-17

- Novel explanation of Chai Songyan’s academic viewpoint of "yangming channels pathogenic theory" in the treatment of polycystic ovary syndrome
- Modern Chinese Clinical Medicine Vol. 29, Issue 5, Pages: 43-47(2022)
- 作者机构：
  
  1.北京中医药大学　北京　100029
  2.北京中医药大学东方医院
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2022.05.010
  CLC： R271.9
- Published：30 September 2022，
  
  Received：14 December 2021，
- 稿件说明：
移动端阅览
WANG Yang, TONG Qing, LIN Qing, et al. Novel explanation of Chai Songyan’s academic viewpoint of "yangming channels pathogenic theory" in the treatment of polycystic ovary syndrome. [J]. Modern Chinese Clinical Medicine 29(5):43-47(2022)
DOI：

WANG Yang, TONG Qing, LIN Qing, et al. Novel explanation of Chai Songyan’s academic viewpoint of "yangming channels pathogenic theory" in the treatment of polycystic ovary syndrome. [J]. Modern Chinese Clinical Medicine 29(5):43-47(2022) DOI： 10.3969/j.issn.2095-6606.2022.05.010.

摘要

“二阳致病”是国医大师柴嵩岩教授在长期临床实践中形成的诊治月经病的特色学术观点。历代医家多认为“二阳”是指十二经脉中手阳明大肠经和足阳明胃经，二阳之病即为胃与大肠疾病。柴教授认为阳明脏腑病变可作为致病因素直接影响女性生理及生殖功能。多囊卵巢综合征以脾肾阳虚为本、痰湿结聚为标。本病患者多为先天不足，或后天失养，而致脾肾阳虚。治疗首先强调祛除致病因素，不急于应用补药，先“解其外衣”，针对标实祛除痰湿、湿热或局部瘀滞，临证用药自成特色，且避免收涩、滋腻药物。

Abstract

Yangming

channels pathogenic theory (

èr yán



zhì bìng

)" is an ingenious academic viewpoint of diagnosis and treatment of menstrual diseases created by Professor Chai Songyan

laureate of the title "Great Master of Traditional Chinese Medicine"

in his decades of clinical practice. Ancient medical experts believe that "

èr yán

" refers to the hand

yangming

large intestine channel and the foot

yangming

stomach channel of the twelve meridians. Therefore

the

yingming

diseases (

èr yán

 diseases) are diseases in the stomach and large intestine. Professor Chai Songyan believes that pathological changes in the

yangming

viscera lesions can directly affect female physiological and reproductive functions as a pathogenic factor. Polycystic ovary syndrome (PCOS) is characterized by deficiency of the spleen and kidney yang

which is the root of the disease

and accumulation of phlegm-dampness as the branch. Patients with PCOS are usually congenitally deficient

or insufficiently nourished in terms of acquired constitution

leading to spleen kidney yang deficiency. The treatment of PCOS emphasizes to remove the pathogenic factors (dispel phlegm

damp heat or local stasis)

rather than applying tonifying medicinals too eagerly

which can be likened to "strip off its coat" first. She has created a unique set of clinical prescriptions

which avoids astringent

enriching and cloying drugs.

关键词

二阳致病多囊卵巢综合征国医大师柴嵩岩

Keywords

yangming channels pathogenic theorypolycystic ovary syndromeGreat Master of TCMChai Songyan

references

GOODARZI M O，DUMESIC D A，CHAZENBALK G，et al.Polycystic ovary syndrome：etiology，pathogenesis and diagnosis[J].Nature Reviews Endocrinology，2011, 7(4): 219-231.

BRUNI V，CAPOZZI A，LELLO S.The role of genetics, epigenetics and lifestyle in polycystic ovary syndrome development：the state of the art[J].Reproductive Sciences，2022, 29(3): 668-679.

谢幸，孔北华，段涛.妇产科学[M].9版.北京：人民卫生出版社，2018: 348.

吴昆.黄帝内经素问吴注[M].孙国中，方向红，点校. 2版.北京：学苑出版社，2012: 44.

丹波元简.中医典籍丛刊：素问识[M].北京：中医古籍出版社，2017: 58-59.

康宁，傅金英.万全妇科二书校注[M].郑州：河南科学技术出版社，2019: 6-7.

滕秀香，濮凌云.柴松岩“二阳致病”学术思想及临床经验解析[J].中医药信息，2015, 32(1): 65-66.

KELLY C，HELEN L，PETRIE J R，et al.Low grade chronic inflammation in women with polycystic ovarian syndrome[J].Journal of Clinical Endocrinology & Metabolism，2001, 86(6): 2453-2455.

MANCINI A，BRUNO C，VERGANI E，et al.Oxidative stress and low-grade inflammation in polycystic ovary syndrome：controversies and new insights[J/OL].International Journal of Molecular Sciences,2021,22(4):1667[2021-11-05].https://doi.org/10.3390/ijms22041667https://doi.org/10.3390/ijms22041667.

MAYER E A.Gut feelings：the emerging biology of gut-brain communication[J].Nature Reviews Neuroscience，2011, 12(8): 453-466.

李玲玲，苏磊，胡梦圆，等.升阳散火汤及其拆方对慢性疲劳综合征小鼠行为学和肠道菌群的影响[J].北京中医药大学学报，2021, 44(10): 908-916.

QI X，YUN C，SUN L，et al.Gut microbiota-bile acid-interleukin－22 axis orchestrates polycystic ovary syndrome[J].Nature Medicine，2019, 25(8): 1225-1233.

LVLL K，ARFFMAN R K，SOLA L A，et al.The gut microbiome in polycystic ovary syndrome and its association with metabolic traits[J].The Journal of Clinical Endocrinology and Metabolism，2020, 106(3): 858-857.

PUTHER F，BOS M P，TOMMASSEN J.Transport of lipopolysaccharide to the Gram-negative bacterial cell surface[J]. FEMS Microbiology Reviews，2015, 39(6): 985-1002.

BOULANGE C L，LUISA N A，JULIEN C，et al.Impact of the gut microbiota on inflammation, obesity, and metabolic disease[J/OL].Genome Medicine,2016,8(1):42[2021-11-05].https://pubmed.ncbi.nlm.nih.gov/27098727/https://pubmed.ncbi.nlm.nih.gov/27098727/.

CHANG Z P，DENG G F，SHAO Y Y，et al.Shaoyao-Gancao decoction ameliorates the inflammation state in polycystic ovary syndrome rats via remodeling gut microbiota and suppressing the TLR4/NF－κB pathway[J/OL].Frontiers in Pharmacology,2021,5(12):670054[2022-07-05].https://pubmed.ncbi.nlm.nih.gov/34054541/https://pubmed.ncbi.nlm.nih.gov/34054541/.

NEWMAN T M，SHIVELY C A，REGISTER T C，et al.Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model[J/OL].Microbiome,2021,9(1):100[2022-07-05].https://pubmed.ncbi.nlm.nih.gov/33952353/https://pubmed.ncbi.nlm.nih.gov/33952353/.

韦航航.多囊卵巢综合征伴慢性低度炎症状态的中医证候分布规律[D].郑州：河南中医药大学，2017.

倪朱谟.本草汇言[M].戴慎，陈仁寿，虞舜，点校.上海：上海科学技术出版社，2005: 575.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Application of Chai Songyan’s "yangming channels pathogenic theory" in the treatment of amenorrhea caused by antipsychotics

Treatment of polycystic ovarian syndrome through the lens of qi

Correlation between pattern features of polycystic ovary syndrome and ovarian morphological and hemodynamic parameters under ultrasonography

The guiding role of CHAI Songyan’s "Four Most of the Kidney" theory in female psychiatric treatment

Clinical research of treating ovulation disorders in polycystic ovary syndrome with endocrine-regulating acupuncture

Related Author

JIA Hongxiao

LI Ziyan

TONG Qing

SHEN Tian

HAO Xiufang

WANG Guohua

HE Xiangyu

XU Xin

Related Institution

Advanced Innovation Center for Human Brain Protection, Capital Medical University

National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University

The Third Affiliated Hospital of Beijing University of Chinese Medicine

Beijing Chinese Medicine Hospital affiliated to Capital Medical University

The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University

⁰

Novel explanation of Chai Songyan’s academic viewpoint of "yangming channels pathogenic theory" in the treatment of polycystic ovary syndrome

DOI：10.3969/j.issn.2095-6606.2022.05.010

摘要

Abstract

关键词

Keywords

references