Objective

2

To analyze the related literature on TCM syndromes of diabetic kidney disease (DKD)

and summarize and discuss the distribution characteristics of DKD TCM patterns.

Methods

2

Relevant literatures from January 1

2016 to January 1

2021 were retrieved in CNKI

Wanfang Data

VIP

and PubMed

and those that meet the inclusion criteria were screened and a database was created for syndrome extraction

name standardization and separation

and syndrome element extraction.

Results

2

We retrieved a total of 1

498 papers

109 of the 127 papers included have TCM diagnostic criteria

and a total of 175 patterns were extracted

which were then standardized into 33 TCM patterns. The top five are: qi-yin deficiency

blood stasis

deficiency of both yin and yang

phlegm-turbidity

deficiency of spleen and kidney qi. From the perspective of

zang

-

fu

pattern differentiation

kidney accounted for the largest proportion of the 33 types

and deficiency patterns is also considerably common

which are all related to kidney deficiency. We extracted 20 pattern elements related to the nature of the disease and 9 associated with disease locations. The association rule analysis of the 20 property-related elements revealed 6 syndrome element combinations. "Blood stasis-qi deficiency" and "dampness-qi deficiency"

which are the most common ones

have top support

and "dampness-blood stasis" combinations have top confidence and improvement and the second is "qi deficiency-dampness" combinations.

Conclusions

2

The TCM patterns of DKD were characterized by a mixture of deficiency and excess; deficiency patterns were dominated by qi-yin deficiency

deficiency of both yin and yang

and deficiency of spleen and kidney qi; excessive patterns mainly include blood stasis and phlegm-turbidity; yin deficiency and qi deficiency were the main pathological factors for the disease.