Objective

2

To analyze clinical experience in treating acne vulgaris based on data mining.

Methods

2

The frequency

classification

efficacy

the four qi

the five flavors and channel tropism of TCM herbal medicine in them were statistically analyzed. Association rules and clustering analysis were used to explore potential herbal ingredient combinations

and data visualization was realized by network diagrams.

Results

2

A total of 395 prescriptions were included in the study

involving 212 ingredients. The most frequently used ones include

Spina Gleditsiae

Radix et Rhizoma Glycyrrhizae

Fructus Forsythiae

Radix Scutellariae

and

Radix Angelicae Dahuricae

. The herbs are mainly cold and warm medicinals in terms of medicinal properties

and bitter

acrid

and sweet in terms of flavors. The meridian that they enter is primarily the spleen meridian. The most frequently seen category is the heat-clearing medicinals

followed by the deficiency-supplementing medicinals

the blood-invigorating and stasis-dissolving medicinals. The mostly seen function of the herbs is tonifying qi

followed by clearing heat and resolving toxins

draining water and reducing swelling

and clearing heat and drying dampness. The herb with a eigenvector centrality of 1 in the complex network graph is

Spina Gleditsiae

followed by

Radix Angelicae Dahuricae

Fructus Forsythiae

Radix Scutellariae

and

Radix et Rhizoma Glycyrrhizae

. Association rule analysis yields 34 combinations of TCM herbal medicine commonly used for acne. In the cluster analysis

3 candidate new prescriptions are obtained.

Conclusion

2

Our team attaches importance to the application of heat-clearing medicine

blood cooling and invigorating medicine when treating acne vulgaris

and also focuses on regulating the spleen and stomach.