TCM prevention and treatment of colorectal cancer based on the theory of reinforcing healthy qi and resolving toxins

HE Shanquan; XU Xinyao; CHEN Xue; LI Weidong; HUA Baojin

doi:10.3969/j.issn.2095-6606.2023.01.019

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TCM prevention and treatment of colorectal cancer based on the theory of reinforcing healthy qi and resolving toxins

更新时间：2023-02-02

- TCM prevention and treatment of colorectal cancer based on the theory of reinforcing healthy qi and resolving toxins
- Modern Chinese Clinical Medicine Vol. 30, Issue 1, Pages: 80-83(2023)
- 作者机构：
  
  1.中国中医科学院广安门医院　北京　100053
  2.中国中医科学院广安门医院科研处
  3.中国中医科学院广安门医院肿瘤科
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2023.01.019
  CLC： R273
- Published：30 January 2023，
  
  Received：03 April 2022，
- 稿件说明：
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HE Shanquan, XU Xinyao, CHEN Xue, et al. TCM prevention and treatment of colorectal cancer based on the theory of reinforcing healthy qi and resolving toxins. [J]. Modern Chinese Clinical Medicine 30(1):80-83(2023)
DOI：

HE Shanquan, XU Xinyao, CHEN Xue, et al. TCM prevention and treatment of colorectal cancer based on the theory of reinforcing healthy qi and resolving toxins. [J]. Modern Chinese Clinical Medicine 30(1):80-83(2023) DOI： 10.3969/j.issn.2095-6606.2023.01.019.

摘要

结直肠癌(CRC)是全球第三大常见恶性肿瘤。基于扶正解毒理论的中医药防治CRC有独特优势。中医药防治肿瘤及其复发转移的关键是提升患者正气，扶正不仅局限于提升患者的免疫系统防御能力，也与改善患者体内或者肠道内的内环境稳态，防止基因突变或提升抑癌基因相关，甚至与抑制肿瘤血管新生、调控肿瘤细胞自噬等机制相关。中医药解毒的机制可能在于改变肠道内部环境，降低炎症引起的氧化应激，防止炎症及氧化应激诱导的DNA突变，抑制肠癌细胞增殖以及促进肠癌细胞凋亡等。基于扶正解毒理论的中医药防治，在防治慢性肠炎癌变、减轻放化疗不良反应、防止CRC复发和转移方面，均有明确疗效。

Abstract

Colorectal Cancer (CRC) is the third most common type of cancer in the world. Traditional Chinese medicine (TCM)

based on its theory of reinforcing healthy qi and resolving toxins

has unique advantages in preventing and treating CRC. The key to the prevention and treatment of cancer and its recurrence and metastasis is to strengthen the healthy qi of the patients. This is not only to improve the immune defense

but also to ameliorate the gut microbiota

prevent gene mutation and enhance expression of cancer suppressor genes. It can be even connected with inhibition of tumor angiogenesis

regulation of autophagy of tumor cells and so on. The mechanism of toxins removal of TCM may lie in the improvement of the intestinal environment

reduction of oxidative stress caused by inflammation

prevention of gene mutation induced by inflammation and oxidative stress

inhibition of the proliferation of colorectal cancer cells

and boosting of their apoptosis. Prevention and treatment by TCM based on the theory of reinforcing healthy qi and resolving toxins have been proven to be effective for preventing the canceration of chronic enteritis

reducing the adverse reactions of radiotherapy or chemotherapy

preventing the recurrence and metastasis of CRC and so on.

关键词

扶正解毒中医药结直肠癌防治

Keywords

reinforcing healthy qiresolving toxinstraditional Chinese medicinecolorectal cancerprevention and treatment

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