Objective

2

To explore pattern distribution characteristics of chronic cough.

Methods

2

A total of 771 chronic cough patients were included. A clinical questionnaire for TCM syndromes of chronic cough designed by us was used to collect four TCM diagnostic information

including TCM symptoms

signs

tongue and pulse. SPSS 22.0 was used for frequency statistical analysis. Pathological factors

positional factors and syndrome distribution characteristics of chronic cough patients were discussed based on the exploratory factor analysis.

Results

2

Thirty six variables with frequency

>

8% were selected from 76 information variables of four diagnostic information

then factor analysis was conducted as observation indexes of four diagnostic information.The KMO value was 0.620 (

>

0.5) and Bartlett ball type test result was

F

=630

P

<

0.001

indicating it was suitable for factor analysis. A total of 12 common factors with initial eigenvalue

>

1 were extracted. The cumulative contribution rate was 59.368%. The common factor scores of 771 cases were calculated by the regression method. Pathological factors of 771 chronic cough patients were wind (77.43%)

dampness-heat (62.13%)

phlegm dampness (35.15%)

Yang deficiency (29.31%)

cold rheum (26.98%) and Yin deficiency (11.41%). Positional factors were the lung (88.98%)

spleen (79.77%)

stomach (39.43%) and kidney(30.35%). Syndrome distribution characteristics of 771 chronic cough patients were wind hidden in the lung pattern (71.85%)

dampness heat retained in the lung pattern (47.86%)

phlegm dampness blocking the lung pattern (25.42%)

cold fluid hidden in the lung pattern (21.14%)

the lung and spleen Yang deficiency pattern (10.89%) and lung Yin deficiency pattern (0.91%).

Conclusion

2

The most common traditional Chinese medicine pattern type of chronic cough is wind hidden in the lung pattern

followed by dampness heat blocking the lung pattern

phlegm dampness blocking the lung pattern

cold rheum hidden in the lung pattern

the lung and spleen Yang deficiency pattern and the lung Yin deficiency pattern. Each pattern can exist alone

but also often coexist with each other. The characteristics of the chronic cough pattern reflect the complicated etiology and pathogenesis of chronic cough. The common pathogenesis of chronic cough is wind hidden in the lung. Pathogenesis characteristics of chronic cough include combination of internal and external pathogenic factors

viscera and bowels interrelated

mixed deficiency and excess. The chronic cough is characterized by a long course of disease

relapsed attacks

protracted and difficult to cure.