Pattern identification and treatment of gastric cancer from the perspective of five-stage evolution

SUN Qianhui; ZHU Xiaoyu; LI Jie; LI Tingting; XU Bowen; MA Xinyi

doi:10.3969/j.issn.2095-6606.2023.02.021

您当前的位置：

首页 >

文章列表页 >

Pattern identification and treatment of gastric cancer from the perspective of five-stage evolution

Ideas and Methodologies | 更新时间：2023-03-31

- Pattern identification and treatment of gastric cancer from the perspective of five-stage evolution
- Modern Chinese Clinical Medicine Vol. 30, Issue 2, Pages: 97-101(2023)
- 作者机构：
  
  1.中国中医科学院广安门医院肿瘤科　北京　100053
  2.北京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2023.02.021
  CLC： R273
- Published：30 March 2023，
  
  Received：13 August 2022，
- 稿件说明：
移动端阅览
SUN Qianhui, ZHU Xiaoyu, LI Jie, et al. Pattern identification and treatment of gastric cancer from the perspective of five-stage evolution. [J]. Modern Chinese Clinical Medicine 30(2):97-101(2023)
DOI：

SUN Qianhui, ZHU Xiaoyu, LI Jie, et al. Pattern identification and treatment of gastric cancer from the perspective of five-stage evolution. [J]. Modern Chinese Clinical Medicine 30(2):97-101(2023) DOI： 10.3969/j.issn.2095-6606.2023.02.021.

摘要

胃癌是全球常见的恶性肿瘤之一，严重威胁人类健康，中医治疗肿瘤具有特色。从根于“中气亏败”、发为“湿热郁积”分析明代新安医家汪机所著《医学原理》中对胃癌病机的阐释。从五期演变探讨胃癌的病机变化：虚——大气虚陷、中轴乏运是发病之本，寒——脾阳虚衰、寒凝阴结是进展之因，毒——气机逆乱、癌毒流窜是转折之核，闭——升降失司、癌毒郁闭是渐坏之征，衰——水火失济、阴阳衰微是终末之根。基于五期演变规律探讨胃癌的辨证论治：癌前状态、早期，治以温阳益气，进展期、术后，治以解毒化浊，晚期、终末期，治以固本通闭。结合临床验案对胃癌的诊疗思路与治疗用药经验进行介绍。

Abstract

Gastric cancer is one of the most common malignant tumors in the world

which seriously threatens human health. The treatment of tumors with traditional Chinese medicine has its own unique characteristics. This paper elucidates the explanation of the pathogenesis of gastric cancer in the

Principles of Medicine

written by Wang Ji

a physician of the Xin’an School in the Ming Dynasty

from its root of "deficiency of middle Qi" and manifestations of "stagnation of dampness-heat" . From the five stages of evolution

the pathogenesis of the gastric cancer is discussed. Deficiency: Deficiency and sinking of Qi and central axis failing to transform are the root of the onset. Cold: Declined spleen deficiency and cold and Yin congestion are the causes of progress. Toxin: Disordered Qi movement and cancerous toxin flow are the core of transition. Closure: loss of control of rising and falling and stagnation of cancerous toxin are the signs of deterioration. Debilitation: Water and fire which fail to support each other and decline of Yin and Yang are responsible for the occurrence of this disease. We explore the syndrome differentiation and treatment of gastric cancer based on the evolution law of the five stages: warming Yang and promoting Qi in the precancerous state and early stage; detoxifying and removing turbidity in the advanced stage and postoperative stage. Combined with clinical cases

the diagnosis and treatment ideas and medication experience of gastric cancer are introduced.

关键词

医学原理五期演变胃癌病机

Keywords

principles of medicinethe five-stage evolutiongastric cancerpathogenesis

references

SUNG H，FERLAY J，SIEGEL R L，et al. Global cancer statistics 2020：GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. Ca Cancer J Clin，2021,71(3): 209-249.

LIU D，LU M，LI J，et al. The patterns and timing of recurrence after curative resection for gastric cancer in China[J]. World J Surg Oncol，2016,14(1): 1-11.

李全耀，施俊，陆颖，等.针灸对胃癌化疗期间不良反应随机对照试验的Meta分析[J].中医肿瘤学杂志，2021,3(6): 77-87.

周云，李朕，杨百京，等.中医健脾养胃法在胃癌治疗中的应用探讨[J].中华肿瘤防治杂志，2018,25(S2): 63-64.

汤汇涓，舒鹏.中医健脾养胃法在胃癌治疗中的应用探讨[J].湖南中医药大学学报，2016,36(4): 42-44.

张澍澄.中医健脾祛瘀法对胃癌术后恢复及生存期的影响效果分析[J].中国医药指南，2019,17(27): 216-217.

许雯雯，张锋利.晚期胃癌的中医药治疗进展[J].中国中医药现代远程教育，2022,20(17): 199-202.

黄智芬，卢旭全，袁颖，等.健脾消积汤联合化疗对老年晚期胃癌患者生活质量及免疫功能的影响[J].中国中医药现代远程教育，2020,18(2): 108-111.

李杰.五期演变——中医药防治恶性肿瘤理论体系构建及创新[J].北京中医药大学学报，2022,45(3): 223-230.

朱潇雨，葛媛莎，李杰.恶性肿瘤“五期演变”规律的生物学基础[J].中国实验方剂学杂志，2022,28(20): 209-217.

汪机.医学原理：上[M].储全根，万四妹，校注.北京：中国中医药出版社，2009.

李时珍.本草纲目：上册[M].北京：中国档案出版社，1999: 72.

周骏，赵智强，刘晓芬.周仲瑛教授论治胃癌术后的经验[J].中医临床研究，2018,10(36): 1-3.

陈赐慧，花宝金.花宝金教授治疗胃癌经验探析[J].世界中西医结合杂志，2013,8(1): 13-15.

肖沛玲.黎月恒教授治疗中晚期胃癌临床经验及学术思想总结[D].长沙：湖南中医药大学，2018.

戴小军，侯超，吴永健，等.基于“脾主运化”理论论治胃癌[J].时珍国医国药，2018,29(7): 1697-1699.

扁鹊.难经[M].北京：科学技术文献出版社，1996: 30.

朱潇雨，吴喆，高瑞柯，等.从“阳虚毒结”角度探讨化疗耐药形成及温阳法干预机理[J].中医杂志，2021,62(8): 672-676.

张锡纯.医学衷中参西录[J].王吉匀，韩煜，潘兴芳，等，整编.石家庄：河北科学技术出版社，2007: 186.

陈群伟，包剑锋.《医学原理》积聚论治经验[J].中华中医药学刊，2012,30(6): 1404-1406.

黄元御.四圣心源[M].孙洽熙，校注.北京：中国中医药出版社，2009.

童凤翔，徐艺.浅谈单兆伟教授治疗慢性萎缩性胃炎经验[J].天津中医药，2021,38(4): 438-441.

吕林，王静，罗仕娟，等.黄穗平治疗慢性萎缩性胃炎经验[J].广州中医药大学学报，2014,31(6): 1002-1004.

张乙，李杰.李杰病证结合辨治胃癌经验[J].中国中医基础医学杂志，2018,24(11): 1639-1641.

杜艳茹，檀书庭，徐伟超，等.李佃贵教授应用浊毒理论治疗慢性萎缩性胃炎临床经验[J].河北中医，2017,39(5): 645-648.

杨志峥.化瘀健脾汤联合FOLFOX4方案治疗胃癌中晚期的临床疗效及对生活质量的影响[J].中医研究，2022,35(1): 43-48.

代海军.半夏泻心汤加减联合SOX方案化疗治疗晚期胃癌临床观察[J].光明中医，2020,35(15): 2376-2378.

Views

160

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

To explore the pathogenesis, outcome and treatment principles of malignant tumor based on the theory of latent oncotoxin

Syndrome differentiation and treatment of recurrent urinary calculi based on combination of disease and syndrome

Application of "body, qi and spirit" theory in hyperthyroidism

TCM pathogenesis and syndrome manifestations of cancer-related fatigue in patients with lung cancer

TCM and Western medicine understandings of pathogenesis of acute pancreatitis based on "obstruction causes pain"

Related Author

WANG Yunxiao

LI Tong

SUN Ying

GAO Chen

SONG Fengli

KANG Ning

QU Yuting

ZHANG Yaosheng

Related Institution

The Third Affiliated Hospital of Beijing University of Chinese Medicine

Dongzhimen Hospitial, Beijing University of Chinese Medicine

Guang’anmen Hospital, China Academy of Chinese Medical Sciences

Beijing University of Chinese Medicine Third Affiliated Hospital

Shenzhen Hospital (Longgang) Beijing University of Chinese Medicine

⁰