Clinical research of traditional Chinese medicine for COVID-19: evidence, issues and challenges

LIU Jianping

doi:10.3969/j.issn.2095-6606.2023.04.003

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Clinical research of traditional Chinese medicine for COVID-19: evidence, issues and challenges

COVID-19 | 更新时间：2023-08-07

- Clinical research of traditional Chinese medicine for COVID-19: evidence, issues and challenges
- Modern Chinese Clinical Medicine Vol. 30, Issue 4, Pages: 12-16(2023)
- 作者机构：
  
  北京中医药大学循证医学中心　北京　100029
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2023.04.003
  CLC： R-03
- Published：30 July 2023，
  
  Received：27 April 2023，
- 稿件说明：
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LIU Jianping. Clinical research of traditional Chinese medicine for COVID-19: evidence, issues and challenges. [J]. Modern Chinese Clinical Medicine 30(4):12-16(2023)
DOI：

LIU Jianping. Clinical research of traditional Chinese medicine for COVID-19: evidence, issues and challenges. [J]. Modern Chinese Clinical Medicine 30(4):12-16(2023) DOI： 10.3969/j.issn.2095-6606.2023.04.003.

摘要

在既往新型冠状病毒感染(简称“新冠感染”)大流行的3年中，中医药从疫情初始便介入了对新冠感染的防控和临床救治，取得令人瞩目的成就。本文总结了中医药预防和治疗新冠感染及其后遗症的临床科研证据的现状及存在问题，并提出紧急公共卫生流行事件下中医药研究的策略，力求为今后疫病的中医药防治提供参考。已有证据显示，中医药有助于预防新冠感染、降低密接者的转阳率、降低新冠感染患者的病毒载量；有助于改善新冠感染症状、缓解炎症、降低重症率、缩短转阴时间；有助于改善长新冠患者的消化道症状和呼吸道症状，提升肺功能。虽然中医药防治新冠感染的研究与成果发表不断增多，但其中包含大量的横断面研究、队列研究、病例报告等低等级证据类型，仍缺乏多中心、大样本、安慰剂对照、双盲设计的随机对照试验以及进一步的系统评价与Meta分析。

Abstract

In the past three years of the COVID-19 pandemic

traditional Chinese medicine has been involved in the prevention and treatment for the viral disease since the beginning of the outbreak

and has made remarkable achievements. This study summarized the progress and existing problems of clinical research of traditional Chinese medicine for COVID-19

and proposed strategies for future TCM studies in case of public health emergency in relation to communicable diseases

to inform practice and policy. Evidence shows that traditional Chinese medicine has potential benefits in COVID-19 prevention

treatment and recovery

may help to reduce the infection rate of close contacts

reduce the viral load; improve the symptoms

relieve inflammation

reduce the rate of progression into severe cases

and shorten the time for viral clearance; improve gastrointestinal and respiratory symptoms and lung function in patients after COVID-19. Although large number of TCM studies on COVID-19 have been published

most of the evidence is of low quality. Therefore

more multi-center

large-sample

placebo-controlled

double-blind randomized controlled trials and related systematic reviews and meta-analyses are needed in the future.

关键词

新型冠状病毒感染临床研究证据中医药

Keywords

COVID-19clinical research evidencetraditional Chinese medicine

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