最新刊期
期 3 ， 2022
- 摘要：ObjectiveThe purpose of this study was to analyze the correlation between TCM constitutions and cervical high-risk human papillomavirus (HR-HPV) infection.Methods203 patients who were routinely screened for HR-HPV were divided into the HR-HPV infection negative group (103 patients) and the HR-HPV infection positive group (100 patients) based on whether they were infected by the virus or not. Basic information such as age, body mass index, education, and marital status were collected from the 2 groups of patients. Univariate logistic regression was used to identify the factors associated with HR-HPV infection. Those with P<0.05 were included in the multivariate logistic regression to determine the independent risk factors associated with HR-HPV infection.ResultsAge, education, marital status, smoking more than 10 cigarettes in a week, condom use, number of pregnancies, number of abortions, number of sexual partners, age of first sexual intercourse, and TCM constitution distribution indexes were the factors that showed statistically significant differences between the 2 groups (P<0.05). Age, smoking more than 10 cigarettes a week, number of pregnancies, number of abortions, number of sexual partners, yang-deficiency type, phlegm-dampness type, blood-stasis type, inherited-special type, and qi-stagnation type of TCM body constitutions were positively correlated with the presence of HR-HPV infection (P<0.05). Education, drinking more than 50 mL of alcohol in a week, and being unmarried were negatively correlated with whether HR-HPV infection was present (P<0.05). The multivariate logistic regression analysis showed that the constitutions of the phlegm-dampness, blood-stasis and inherited-special types were independent risk factors for HR-HPV infection compared with the balance constitution.ConclusionsThere is a correlation between TCM constitutions and the occurrence of HR-HPV infection.关键词：high-risk human papillomavirus;traditional Chinese medicine constitution;logistic regression
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发布时间：2022-06-02 - 摘要：ObjectiveTo observe the effect of filiform needle therapy and bian paste therapy on blood perfusion at acupoints of of the hand jueyin pericardium channel.MethodsForty-five healthy subjects were randomly divided into bian paste group (n=15), filiform needle group (n=15) and control group (n=15). Laser speckle imaging for microcirculation blood flow measurements was used to observe the blood perfusion at the selected acupoints.ResultsThe blood flow perfusion at Neiguan (PC 6) of the subjects in the control group decreased during the experiment, and the difference was statistically significant (F=2.995, P<0.05). The blood perfusion at this location at 12 min of intervention and 4 min post-intervention was significantly lower than that of 4 min pre-intervention (P<0.05). In the filiform acupuncture group, the blood flow perfusion at Neiguan increased with the intervention time, and the difference was statistically significant (F=10.042, P<0.05). The blood flow at this acupoint at 0 min of intervention, 4 min of intervention, 8 min of intervention, 12 min of intervention, 16 min of intervention and 4 min post-intervention were significantly higher than those before intervention (P<0.05). The blood perfusion at Neiguan at 16 min of intervention and 4 min post-intervention was significantly higher in the filiform needle group than that in the bian paste group and the control group (P<0.05). The blood perfusion at Jianshi (PC 5), Ximen (PC 4), non-acupoint locations on the channel, and non-acupoint locations in non-channel areas in the control group decreased as the intervention progressed, and the differences were statistically significant (P<0.05). In the bian paste group, the blood perfusion at Ximen decreased with the intervention time, and the difference was statistically significant (F=2.346, P<0.05). The blood perfusion at this acupoint at 0 min of intervention, 4 min of intervention and 12 min of intervention was significantly lower than that of 4 min pre-intervention (P<0.05).ConclusionsBoth filiform needle therapy and bian paste therapy can increase skin blood perfusion at the selected acupoints on the hand jueyin pericardium channel, but each has its own pattern of regulating microcirculation.关键词：bian paste therapy;filiform needle therapy;pericardium channel;Neiguan (PC 6);blood perfusion of skin
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发布时间：2022-06-02 - 摘要：ObjectiveTo explore the characteristics of Feng’s spine-pinching manipulation by measuring the effect of different manipulations and positions of pinching on the secretion of ghrelin and leptin, two factors that affect appetite, of children with anorexia.Methods102 children were randomly divided into three groups: 46 in the group of Feng’s spine-pinching manipulation (the Feng’s group), 42 in the group of the "three-finger" spine-pinching manipulation (the three-finger group) and 39 in the control group (manipulations conducted at locations that are not the acupoints targeted by the Feng technique). After those who dropped out were removed, there were 37 patients in the Feng’s group, 35 in the three-finger group, and 30 in the control group. Their levels of ghrelin and leptin were measured before and after treatment, along with other indicators including symptom scale score, clinical efficacy, height, weight, BMI, and safety assessment.ResultsA comparison of ghrelin levels of children in the three groups reveals that ghrelin levels in both the three-finger and control groups increased compared to their respective pre-treatment levels, and the differences were statistically significant (P<0.05). The differences before and after treatment in the three groups were statistically significant (P<0.05). Compared with the control group, the difference of ghrelin level in the Feng’s group before and after treatment was lower, and the difference was statistically significant (P<0.05). The post-treatment leptin level in the control group decreased compared with that before treatment, and the difference was statistically significant (P<0.05). The respective differences in the symptom scale scores in the 3 groups before and after treatment were statistically significant (P<0.05). Compared with the control group, the difference between the pre- and post-treatment symptom scale scores was lower in the Feng’s group, and the difference was statistically significant (P<0.05). Compared with the Feng’s group, the difference between pre- and post-treatment was lower in the symptom scale scores in the three-finger group, and the difference was statistically significant (P<0.05). Spearman’s rank correlation analysis of the post-treatment indicators showed a positive correlation between ghrelin levels and age of the children after treatment (r=0.248, P=0.012).ConclusionsFeng’s spine-pinching manipulation can effectively promote dietary intake and/or digestion to increase the BMI or fat content.关键词：Feng’s spine-pinching manipulation;anorexia;ghrelin;leptin;BMI;randomized control
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发布时间：2022-06-02 - 摘要：The liver is the unyielding viscus, which governs the free flow of qi and stores the blood. It is yin in form but yang in function, and prefers free activity. Professor Tian Delu has developed his academic theory on relieving digestive diseases by treating liver problems, which can be categorized into the following aspects: 1. It is suggested to soothe the liver and rectify qi when the free movement of qi is restricted due to liver constraint, to unblock the liver collaterals for diseases caused by qi stagnation and blood stasis, and to emolliate the liver in the case of disharmony between its form and function. 2. The liver and spleen should be regulated simultaneously for wood-earth diseases, the principles for which include banking up the earth to relax the liver, banking up the earth to discharge the wood, banking up the earth to dissipate the liver; discharging the liver to harmonize the stomach, and discharging and directing downward liver qi. 3. If hyperactivity of the liver hurts the lung, causing coughing, wheezing and panting, like metal is sounded by the blows of wood, measures should be taken to inhibit liver qi.关键词：syndrome and therapeutic principles of liver qi;famous physicians’ experience;Tian Delu
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发布时间：2022-06-02 - 摘要：Enuresis is defined as urinary incontinence during sleep in a child at least five years of age. Based on her decades of clinical experience, Professor Wang Sumei believes that the disease is located in the kidney and bladder, but fundamentally it is closely related to the liver. As TCM theories suggest, "the liver is often in superabundance" , which is the pathogenesis basis of liver qi stagnation transforming into heat, leading eventually to enuresis. She puts forward that the treatment should start from the liver, with clearing the fire and purging the excess in the liver and gallbladder as the primary method, supplemented by tonifying the kidney and securing and astringing, reducing urination and arresting enuresis. In addition, parents should pay attention to intervention and conditioning at home.关键词：enuresis;traditional Chinese medicine;famous physicians’ experience;Wang Sumei
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发布时间：2022-06-02 - 摘要：Sick sinus syndrome is a disease caused by lesions of the sinus nodes and its surrounding tissues. Professor Guo Weiqin has unique insights into the diagnosis and treatment of sick sinus syndrome. She takes the deficiency in the root and excess at the tip as its basic pathogenesis. Root here is deficiency of yang in the heart, spleen and kidney characterized by slow pulse while the tip here is blood stasis and phlegm blocking the heart, characterized by the alternations between bound pulse and skipping pulse. Therapeutic principles mainly include the following points: reinforcing healthy qi to promote blood circulation, and strengthen the heart; warming yang and unblocking vessels, with equal attention to zang-fu organs and meridians; attaching importance to disease differentiation, promoting blood circulation, removing blood stasis and dispelling wind; balancing chinese herbal medicine property by nourishing yin at the same time. She created Fudou Mixture to treat sick sinus syndrome and modified the formula according to different symptoms, with remarkable effects.关键词：sick sinus syndrome;reinforcing qi and warming yang;famous physicians’ experience;Guo Weiqin
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发布时间：2022-06-02 - 摘要：TCM believes that the root of epilepsy lies in the brain, which is induced by pathological products such as wind, phlegm, fright, blood stasis, etc. resulting in the obstruction of the collaterals and thus the disease. Based on the theories of "when the qi of the gallbladder rises, all the qi of the other eleven zang-fu organs will follow" and "children are born with an immature yang constitution" , Professor Xu Rongqian has developed a unique system of treating epilepsy in children from the perspective of the gallbladder, in which he attaches special attention to the interaction between the gallbladder and the brain, and between the gallbladder and wind, phlegm, fright, and blood stasis. The method of soothing the gallbladder and promoting qi movement should be used throughout the treatment both during and after seizures.关键词：epilepsy in children;traditional Chinese medicine therapy;treatment from the perspective of the gallbladder;famous physicians’ experience;Xu Rongqian
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发布时间：2022-06-02 - 摘要：Acquired immunodeficiency syndrome (AIDS) is one of the major diseases that seriously threaten global public health due to its high infectivity and incurability. After entering the human body, HIV first attacks the
T lymphocytes. Since the gut-associated lymphoid tissue (GALT) is the largest mass of lymphoid tissue in the body, HIV tends to accumulate in the intestinal tract and destroy T lymphocytes there, resulting in the dysbiosis of intestinal flora of the patient, leading to a series of opportunistic infections and related diseases. In the early stage of HIV infection, the number of T cells in the intestine decreases rapidly and massively, and the CD4/CD8 ratio decreases as well, causing immune disorders of the intestinal mucosa. The asymptomatic stage of HIV infection is characterized by chronic immune activation. The stable number of T lymphocytes in some important parts of the body and the balance of intestinal flora may be important factors affecting the progression of the disease. The spleen, which governs transportation and transformation, can play a crucial role in the recovery of the damaged intestinal flora and its function in host nutrient metabolism. By fortifying and activating the spleen, Traditional Chinese Medicine (TCM) can effectively regulate the intestinal flora and facilitate the immune reconstitution of AIDS patients. 关键词：AIDS;traditional Chinese medicine;intestinal flora;intestinal mucosa;immune function- 28
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发布时间：2022-06-02 - 摘要：Pulmonary fibrosis (PF) is characterized by progressive dyspnea, cough, and hypoxemia. TCM theories believe the occurrence and progress of PF are always inseparable from the lung and kidney, so the simultaneous dysfunction of the two organs is one of the crucial features of the disease. This study explores the lung-kidney correlation in PF based on the theory of visceral manifestation, which reveals that lung deficiency is the primary cause and the kidney deficiency is an important pathogenic factor. Pathogenesis and etiology of PF means: dysfunction of wei qi (defensive qi), abnormalities in the ascending and descending of qi, and blood stasis and phlegm coagulation caused by lung and kidney deficiency. Syndrome differentiation and treatment include: for the deficiency of both lung and kidney, it is advisable to suffice and nourish the both to control the deficient and floating qi; for the mixture of deficiency and excess in both organs, it is appropriate to supplement deficiency to relieve the excessive syndrome; for the pattern of kidney deficiency and lung excess, it is suggested to supplement the kidney and to clear the lung, to control the counterflow of Chong qi (from the Chong meridian); for the kidney deficiency due to evil persistence, it is better to warm the kidney to disperse the exterior, to banish the evil of external disturbance. Generally, we should focus on dispelling stasis, resolving toxin and clearing heat; emphasizing the integration of the five zang organs throughout the treatment, and finally restoring the qi-governing function of the lung.关键词：Lung-kidney correlation;pulmonary fibrosis;simultaneous treatment of the lung and the kidney;treatment based on differentiation of syndromes
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发布时间：2022-06-02 - 摘要：Small airways belong to the qi collateral of the lung collaterals, and their damages may result in abnormalities of the entire lung collateral system, and its physiological functions. Small airways obstruction is the early stage of chronic obstructive pulmonary disease (COPD), for which smoking has been recognized as one of the main risk factors. Based on a combination of the theory of "toxic" pathogen and of pulmonary collateral diseases, this study proposes that tobacco smoke is the driving factor of this disease. The injury of lung collaterals by tobacco smoke is manifested in its effect on small airways, which mediates airway inflammation, mucus secretion and eventual obstruction of the passages. Tissue damage in the lungs are caused by smoke invading qi collaterals, which mainly involves the stages smoke evil accumulating in the qi collaterals until toxic levels, the smoke toxins inducing collateral damage, and new toxins result ing from the damaged collaterals. For the treatment, the focus should be placed on removing the toxins and unblocking the collaterals, tonifying qi and nourishing yin. At the initial stage, it is advisable to clear the lungs, moisten collaterals and expel the toxins. At the second stage, the key is to nourish qi and unblock the collaterals and remove the toxins. To deal with the new toxins generated in the third stage, it is suggested to remove stasis, dissolve phlegm and unblock the collaterals.关键词：chronic obstructive pulmonary disease;small airway obstruction;smoking;toxic damage to lungs;the theory of "toxin";the theory of collateral disease
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发布时间：2022-06-02 - 摘要：A Wagner Grade 0 diabetic foot is the early stage of the condition, which suggests that the patient develops diabetic peripheral neuropathy and/or peripheral vascular disease without foot ulcers. TCM theories believe that "disharmony of qi and blood" is the root of Wagner Grade 0 diabetic feet. Its etiology and pathomechanism include: qi and blood depletion, yin impairment affecting yang, deficiency as the root; qi stagnation and blood stasis, blockage of meridians, excess as the branch; weakness of wei qi, disharmony of ying-blood, and subsequent susceptibility to exogenous pathogens; external invasion, worsening deficiency of qi and blood, which aggravates the disease. The key to the treatment is to treat the root by regulating qi and blood, balancing yin and yang, boosting qi and supplementing blood, to treat the branch by moving qi and invigorating blood, dissolving stasis and dredge collaterals, and, for those significantly weakened by the disease and thus unable to withstand the power of the medications, to reinforce healthy qi before dispelling evil.关键词：qi and blood theory;Wagner Grade 0 diabetic foot;diabetic peripheral neuropathy;diabetic peripheral angiopathy;theoretical discussion
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发布时间：2022-06-02 - 摘要：Pulmonary nodules are focal, round-like, solid, or sub-solid radiographic opacities that measures up to 3 cm. Pulmonary nodules can turn out to be cancerous. TCM theories believe that the basic pathogenesis of the condition is stagnation of lung qi, stasis of body fluids, and blockages of collaterals. In this framework, qi, phlegm, and stasis are the key pathological factors, and the main causes of pulmonary nodules are exogenous pathogens attacking the lungs or emotional discomfort, damaging the lung collaterals, the main location of the disease. In clinical practice, the basic method is unblocking collaterals and dissipating masses with acrid-warm medicinals. Shegan Mahuang Decoction is selected as the representative formula and adjusted as needed for different syndromes, to improve the clinical efficacy.关键词：pulmonary nodules;unblocking collaterals and dissipating masses with acrid-warm medicinals;Shegan Mahuang Decoction
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发布时间：2022-06-02 - 摘要：Diaphragm dysfunction refers to a diaphragm thickening fraction less than 30% during exhalation and inhalation. It is a disease characterized by shortness of breath, difficult weaning, and decreased diaphragm thickness. Invasive mechanical ventilation is the most common cause of diaphragmatic dysfunction, which leads to difficulty in weaning the patient from the ventilator and severely affects the prognosis. Therefore, it is crucial to explore under the guidance of traditional Chinese medicine theories the pathomechanism for diaphragm dysfunction induced by invasive mechanical ventilation for its treatment using TCM approaches. Based on the clinical manifestations, the condition belongs to the categories of "dyspnea disorder" and "flaccidity disorder" , with deficiency in lung, spleen and kidney as the root. Therefore, the treatment should follow the principle of supplementing the lungs and fortifying the spleen and kidney.关键词：diaphragm dysfunction;invasive mechanical ventilation;dyspnea disorder;flaccidity disorder;supplementing the lungs, fortifying the spleen and kidney
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发布时间：2022-06-02 - 摘要：Chronic subjective dizziness (CSD) is a clinical syndrome with psychosomatic interaction result ing from the combined effect of vestibular dysfunction and psychiatric disorders, and falls in traditional Chinese medicine into the category of "vertigo" , while being closely related to "stagnation syndrome" . This kind of vertigo is induced by the disorders of the liver, spleen and kidney, with conditions of the liver being the primary cause. Therefore, TCM treatment focus on resolving the liver problem by tonifying qi and blood, and removing phlegm and stasis. However, in the clinical treatment of CSD, it was found that in addition to the chronic vertigo symptoms, most of the patients also had jueyin syndromes, which is characterized by cold and heat in complexity. Therefore, Mume Pill, as the main prescription for the treatment of jueyin syndromes in Zhang Zhongjing’s Treatise on Cold-Induced Diseases, could be used for treating CSD.关键词：chronic subjective dizziness;anxiety and depression;jueyin syndrome
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发布时间：2022-06-02 - 摘要：Endometriosis is a common yet complex gynecological condition, which can take a serious toll on the life quality of the patients. In the Traditional Chinese Medicine (TCM) framework, it falls into the category of "abdominal mass (zhēng ji)" and "accumulation-gathering (jī jù)" . The theory of "yang transforms into qi, while yin constitutes form (yáng huà qì, yīn chéng xíng)" has significant implications for the occurrence and progression of this disease. An interpretation of endometriosis based on this theory reveals that the dysfunction of yang to transform qi, which leads to the inability to warm and dissolve qi, blood, essence, and body fluids, induces excessive constituting of form by yin, resulting in the gathering and accumulation of tangible things in the body, i.e. abdominal masses. Guided by the theory, we conclude that the fundamental pathogenesis of endometriosis is yang deficiency and blood stasis, which lead to insufficient warming and transformation of qi and subsequent accumulation of pathological products such as blood stasis. The treatment should follow the principle of warming yang and removing blood stasis to restore the balance of yin and yang of the body. Clinical cases together with details about the prescriptions are also presented in this study.关键词：endometriosis;yang transforming into qi, yin constituting the body;warming yang and dispersing blood stasis
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发布时间：2022-06-02 - 摘要：The reproductive function of males is based on the essence stored in the kidney which is a comprehensive manifestation of the coordinated functioning of zang-fu organs, qi and blood, body fluids, and meridians, and which is closely related to the qi transformation of the five zang organs. Only when the qi transformation acts properly can the male be able to impregnate. Abnormalities in the qi transformation of the five zang organs will inevitably impair the essence for reproduction, thereby leading to infertility.In clinical practice, syndrome differentiation and targeted treatment are essential for male sterility: for the imbalance of yin and yang in the kidney, the key is to restore the yin-yang harmony; for the frenetic stirring of heart fire, to clear it and nourish the kidney; for the imbalance of qi and blood in the liver, to rectify qi and regulate the blood; for the spleen deficiency and dampness obstruction, to fortify the spleen and dispel dampness; for the disorder of the ventilated and descent functions of the lung, to regulate and tonify the lung and the kidney.关键词：male infertility;five zang organs;qi transformation
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发布时间：2022-06-02 - 摘要：Zhang Xichun, a famous doctor in modern times, had a wealth of academic experience and a thorough understanding of China and the West. His book Records of Chinese Medicine with Reference to Western Medicine elaborated on the differentiation and treatment of heart palpitations and zhēng chōng(severe palpitations). He mainly discussed palpitations from eight aspects: stomach heat in Yangming, hyperactivity of liver qi, internal disturbance of phlegm heat, heart-blood stasis, heart-blood deficiency, pectoral qi collapse, kidney-yin deficiency, and yang-deficiency fluid retention. Zhang argued that a weakened heart was the core pathogenesis, and lack of heart qi and blood was the root of the disease. He proposed the priority of treatment should be given to replenishing qi and blood. He held that the the affected area of palpitations was in the heart, but it was closely related to the spleen, stomach, liver, and kidneys. Despite disease locations, disordered qi activities were the basic disease mechanism. The treatment should focuse on qi regulation. Precise treatment and detailed prescriptions listed in the book are still of important guiding significance for clinical practice.关键词：Records of Chinese Medicine with Reference to Western Medicine;Zhang Xichun;palpitation;experience of diagnosis and treatment
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发布时间：2022-06-02
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