最新刊期
期 5 ， 2022
- 摘要：ObjectiveTo investigate the genetic characteristics of children with persistent and chronic immune thrombocytopenia (ITP) who did not respond well to first-line treatment, and to evaluate the clinical efficacy of Fuzheng Jiedu Decoction (Healthy Qi Reinforcing and Toxin Resolving Decoction) on children with pathogenic gene mutations.MethodsThe 40 children were divided into a mutation group of 17 and a control group of 23 according to their presence or absence of pathogenic gene mutations associated with thrombocytopenia. The result of gene sequencing, clinical efficacy, platelet count, bleeding grade, TCM syndrome score and TCM syndrome efficacy were observed.ResultsAmong the 40 children, 17 (42.50%) had pathogenic or suspected pathogenic gene mutations related to thrombocytopenia, and related diseases included HT, PID, and von Willebrand disease. After 3 months of treatment, there was no significant difference in the clinical efficacy between the two groups (P>0.05). There was no statistically significant difference in platelet count between the two groups at the same time point (P>0.05), but there was a statistically significant difference at different time points (P<0.05). With the increase of treatment time, the platelet count gradually increased. After 1 month of treatment, the TCM syndrome scores of the two groups gradually decreased, and the difference was statistically significant at different time points (P<0.05); there was no significant difference in the TCM syndrome scores between the two groups (P>0.05); the interaction between group and time was not statistically significant (P>0.05). After 3 months of treatment, there was no significant difference in the improvement of bleeding grade and the efficacy of TCM syndromes between the two groups (P>0.05).ConclusionsChildren with persistent and chronic ITP who have grown dependency on first-line treatment or for whom first-line treatment has proven to be ineffective should actively improve gene sequencing and re-evaluate clinical diagnosis and treatment. Fuzheng Jiedu Decoction has a good effect of increasing platelet count, and is more effective in improving bleeding symptoms and TCM syndromes.关键词：children;immune thrombocytopenia;genetic testing;Fuzheng Jiedu Decoction;clinical efficacy
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发布时间：2022-10-17 - 摘要：ObjectiveTo observe the effect of a TCM hip bath formula on postoperative wound healing of patients with anorectal diseases characterized by damp-heat pouring downward.Methods92 patients with anorectal diseases characterized by damp-heat pouring downward who have undergone operations were randomly divided into the treatment group (46 cases) and the control group (46 cases). The treatment group was given hip baths and the control group was treated with 3% boric acid solution. The clinical efficacy, wound healing rate, wound healing time, clinical symptom scores (perianal wound pain, wound exudation and wound edema scores), serum C-reactive protein (CRP) level, wound fibroblast content and wound collagenous fiber area were observed.ResultsIn the treatment group of 46 cases, 28 cases were cured, 12 cases were significantly effective, 4 cases were effective, 2 cases were ineffective, and the total effective rate was 95.65%; In the control group of 46 cases, 24 cases were cured, 8 cases were significantly effective, 5 cases were effective, and 9 cases were ineffective. The total effective rate was 80.43%. The rank sum test showed Z=-2.237, P=0.025, indicating that the clinical efficacy of the treatment group is significantly better than that of the control group. The wound healing rate of the treatment group was better than that of the control group on the 7th and 14th day after operation, and the difference was statistically significant (P<0.05). The wound healing time in the treatment group was (13.41±4.86) d, and that in the control group was (15.76±5.31) d, suggesting that it took a significantly shorter amount of time for the treatment group to heal than for the control group, and the difference was statistically significant (P<0.05). The comparison of perianal wound pain scores between the two groups at different times after operation showed that from the third day after operation, the perianal wound pain scores of the two groups gradually decreased, and the differences between the various time points was statistically significant (P<0.05); There was significant difference in the pain scores of perianal wounds between the two groups (P<0.05). The pain scores of perianal wounds in the treatment group was significantly lower than that in the control group; With the extension of treatment time, the pain scores of perianal wounds in the treatment group and the control group decreased differently, and the treatment group was significantly better than the control group (P<0.05). The comparison of perianal wound exudation scores between the two groups at different times after operation showed that from the third day after operation, the perianal wound exudation scores of the two groups gradually decreased, and the difference between different time points was statistically significant (P<0.05); There was significant difference in perianal wound exudation scores between the two groups (P<0.05). The perianal wound exudation scores of the treatment group was significantly lower than that of the control group; With the extension of treatment time, the reduction of perianal wound exudation scores in the treatment group and the control group was different, and the treatment group was significantly better than the control group (P<0.05). The comparison of perianal wound edema scores between the two groups at different times after operation showed that the perianal wound edema scores of the two groups gradually decreased from the third day after operation, and the difference between different time points was statistically significant (P<0.05); There was significant difference in perianal wound edema scores between the two groups (P<0.05). The perianal wound edema scores of the treatment group was significantly lower than that of the control group; With the extension of treatment time, the reduction of perianal wound edema scores in the treatment group and the control group was different, and the treatment group was significantly better than the control group (P<0.05). Comparison of serum CRP levels in the two groups at different times after operation: from the third day after operation, the serum CRP levels in the two groups gradually decreased, and the difference between different time points was statistically significant (P<0.05); There was significant difference in the level of serum CRP between the two groups (P<0.05). The perianal serum CRP in the treatment group was significantly lower than that in the control group; With the extension of treatment time, the reduction of serum CRP in the treatment group was different from that in the control group, and the treatment group was significantly better than that in the control group (P<0.05). The number of fibroblasts under microscope in the treatment group was (75.24±18.86) and that in the control group was (42.67±16.75), indicating that the treatment group was significantly better than the control group, and the difference was statistically significant (P<0.05). The area of collagen fibers under microscope in the treatment group was (31.37±8.00)% and that in the control group was (23.47±8.29)%, indicating that the treatment group was significantly better than the control group, and the difference was statistically significant (P<0.05).ConclusionsThe hip bath can promote wound healing of patients with anorectal diseases characterized by damp-heat pouring downward, relieve postoperative related symptoms, and shorten wound healing time.关键词：postoperative care of anorectal diseases;TCM hip bath formula;wound healing;damp-heat pouring downward
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发布时间：2022-10-17 - 摘要：ObjectiveTo analyze the factors and TCM patterns of lung cancer-related depression.Methods We collected basic information, which included gender, age, ethnicity, occupation, education, annual household income, source of medical expenses, and tumor-related information, including disease duration, clinical stages, previous treatment, treatment duration, adverse reactions, cancer pain, to what extent are they informed of their conditions, TCM patterns, and depression status, of 160 patients with primary lung cancer. A univariate analysis was conducted through a χ2 test, which screened out the factors with P<0.05, and the logistic regression model was adopted in the multivariate regression analysis to determine the independent factors. Then the relationship between their TCM patterns and severity of depression was analyzed in a χ2 test.ResultsAmong the 160 patients, 68 had a standard score of ≥50 on the Self-Rating Depression Scale, and the incidence of depression was 42.5%. Nine factors, including age, gender, education, clinical stages, previous treatment, adverse reactions to treatment, cancer pain, informedness, and TCM patterns, are associated with lung cancer-related depression (P<0.05). Seven of the nine factor, which are education, clinical stages, previous treatment, adverse reactions to treatment, cancer pain, informedness, and TCM patterns, have statistically significant effects on lung cancer-related depression (P<0.05), and these are independent factors of lung cancer-related depression. Three factors, including TCM patterns, clinical stages and informedness, are closely related to the occurrence of lung cancer-related depression, and education has relatively little effect on lung cancer-related depression. There is a correlation between the severity of depression and the distribution of TCM patterns (P<0.05). Patients with mild depression are mainly characterized by binding constraint of liver qi and phlegm-dampness forming obstructions. Those with moderate depression reported liver constraint and spleen deficiency, and qi stagnation and blood stasis. Patients suffer from severe depression tend to have the pattern of liver-kidney depletion.ConclusionsEducation, clinical stages, previous treatment, adverse reactions to treatment, cancer pain, informedness, and TCM patterns were independent factors of lung cancer-related depression.关键词：lung cancer-related depression;factors;TCM patterns
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发布时间：2022-10-17 - 摘要：Climacteric syndrome is also known as menopausal symptoms, which refers to a series of symptoms before and after menopause. Prof. Han Xuejie believes that the onset of menopause is driven by the deficiency of kidney qi and the gradual exhaustion of tin gǔi (reproduction-stimulating essence), resulting in the imbalance of yin and yang of the viscera, as well as qi and blood irregularities, which are the key pathogenesis of the disease, and further based on clinical manifestations including dysfunction of the liver, heart, spleen, lung and other viscera. The clinical treatment follows the etiology and pathogenesis view of "imbalance of yin and yang, and irregularities of qi and blood" , the disease syndrome treatment view of "concurrent disorder of the five viscera with kidney deficiency as the root" and the efficacy improvement and relapse prevention view of "regulating the liver and resolve constraint, enhanced by TCM psychotherapy" .关键词：climacteric syndrome;clinical thoughts;kidney deficiency;famous physician’s experience;Han Xuejie
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发布时间：2022-10-17 - 摘要：Professor Liu Jingyuan has been mainly engaged in the teaching and studying of warm diseases, and he has accumulated rich clinical experiences in the treatment of internal miscellaneous diseases, especially spleen and stomach diseases, for which he had unique insights and understandings. Based on the physiologic and pathological characteristics of the spleen and the stomach, he puts forward three method for spleen-stomach related diseases: reinforcing the middle energizer and strengthening the vital energy to invigorate the spleen and stomach and replenish qi; invigorating the spleen and nourishing the stomach to ascend yang of the spleen and descend qi of the stomach; ascending lucidity and descending turbidity of the body to regulate the movement of qi. The clinical prescriptions of Professor Liu have the following characteristics: he is expert at using Huangqi Jianzhong Decoction (Astragalus Center-Fortifying Decoction) to reinforce the middle energizer and strengthen the vital energy; in accord with the principle of "pungent for dispersion and bitter for descending" , he also uses Wuwei Zhisuan Decoction (Five-Ingredient Acidity-Reducing Decoction), which brings extraordinary clinical effect in the treatment of hyperacidity. The formula treats both the symptoms and causes and contains only five ingredients: cuttlebone, thunberg fritillary bulb, coptis, medicinal evodia fruit and calcined arc shell.关键词：spleen and stomach diseases;famous physician’s experience;Liu Jingyuan
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发布时间：2022-10-17 - 摘要：Membranous nephropathy is one of the major pathological types of primary glomerular diseases. Membranous nephropathy of unknown etiology is called idiopathic membranous nephropathy (IMN). Deficiency of the spleen and kidney was previously considered as the fundamental of IMN. With smog emerging as an inducing factor, the dysfunction of the lung, spleen and kidney has become the core pathogenesis of IMN. With a thin taste, wind medicinals has the characteristics of raising, dispersing, promoting, stirring, scurrying, and unblocking. On the basis of syndrome differentiation, the addition of wind medicinals can help the lung to disperse and descend, aid the spleen to ascend the nutrients, promote the qi transformation function of the kidney, dispel pathogenic wind, dissipate dampness, invigorate blood, and remove meridian obstruction, thus enhancing the curative effect. Based on the new progress of etiology and pathogenesis of IMN, this paper discusses the efficacy of wind medicinals, with the aim of guiding clinical application.关键词：wind medicinal;smog;lung, spleen and kidney;idiopathic membranous nephropathy;etiology and pathogenesis
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发布时间：2022-10-17 - 摘要：Endometriosis (EMT) is a common hormone-dependent disease of women of childbearing age. Dysmenorrhea is one of the typical clinical manifestations of EMT, which belongs to the category of "blood syndrome" in TCM. Based on the theory of "removing blood stasis is always as the key of all blood syndromes" , combined with the etiology and pathogenesis of the condition, it is pointed out that the treatment of EMT dysmenorrhea should mainly focus on blood circulation and removing blood stasis, warming yang and relieving pain. Hupo Powder has the effect of promoting blood circulation and removing blood stasis, warming yang and relieving pain, and has significant curative effect on gynecological diseases caused by cold blood stasis. This paper provides a detailed explanation of the clinical application of the formula with actual cases.关键词：Hupo Powder;endometriosis;dysmenorrhea;blood syndrome;remove blood stasis
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发布时间：2022-10-17 - 摘要：Myelodysplastic syndrome (MDS) is a malignant clonal disease of acquired hematopoietic stem cells. According to the symptoms of high-risk MDS in the elderly, it belongs to the category of suǐ dú láo (marrow poisoning and fatigue) in traditional Chinese medicine. Its etiology and pathogenesis are based on deficiency of the spleen and kidney, coupled with blood stasis and other pathogenic factors. Clinical principle of syndrome differentiation and treatment: detoxification and removing blood stasis as the core, tonifying spleen and kidney as the foundation; the approach of regulating and tonifying the spleen and stomach, and soothing liver and regulating qi is also emphasized. The combined use of cold and heat medicinals is key in the treatment, and special attention is given to maintaining the yin and yang balance. This paper summarizes the experience of diagnosis and treatment of elderly high-risk MDS based on clinical case records.关键词：myelodysplastic syndrome;marrow poisoning and fatigue;tonifying the kidney and invigorating the spleen;Qinghuang Powder
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发布时间：2022-10-17 - 摘要：The theory of "the liver governs the sinews" was first seen in Wěi Lùn (Discourse on Flaccidity) of Sù Wèn (Basic Questions).This paper hypothesizes based on TCM theory that the liver’s physiological functions of storing blood and governing the free flow of qi are realized through its regulation of the sinews, and we propose a biological interpretation of "the liver governs the sinews" . Firstly, this theory is the basis of the liver’s function of storing blood. Since blood vessels are places where blood is stored, if the vascular smooth muscle which is regarded as "the sinews" in TCM theory is the executor of regulating blood allocation, then the liver can be seen as the regulator of the vascular smooth muscles. Secondly, this theory is also the foundation of "the liver governs the free flow of qi" . The liver can regulate the smooth muscle of viscera to transport essence, this is important for maintaining normal physiological activities of the human body.关键词：the liver governs the sinews;the liver stores the blood;the liver governs the free flow of qi;smooth muscle
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发布时间：2022-10-17 - 摘要："Yangming channels pathogenic theory (èr yán zhì bìng)" is an ingenious academic viewpoint of diagnosis and treatment of menstrual diseases created by Professor Chai Songyan, laureate of the title "Great Master of Traditional Chinese Medicine" , in his decades of clinical practice. Ancient medical experts believe that "èr yán" refers to the hand yangming large intestine channel and the foot yangming stomach channel of the twelve meridians. Therefore, the yingming diseases (èr yán diseases) are diseases in the stomach and large intestine. Professor Chai Songyan believes that pathological changes in the yangming viscera lesions can directly affect female physiological and reproductive functions as a pathogenic factor. Polycystic ovary syndrome (PCOS) is characterized by deficiency of the spleen and kidney yang, which is the root of the disease, and accumulation of phlegm-dampness as the branch. Patients with PCOS are usually congenitally deficient, or insufficiently nourished in terms of acquired constitution, leading to spleen kidney yang deficiency. The treatment of PCOS emphasizes to remove the pathogenic factors (dispel phlegm, damp heat or local stasis), rather than applying tonifying medicinals too eagerly, which can be likened to "strip off its coat" first. She has created a unique set of clinical prescriptions, which avoids astringent, enriching and cloying drugs.关键词：yangming channels pathogenic theory;polycystic ovary syndrome;Great Master of TCM;Chai Songyan
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发布时间：2022-10-17 - 摘要：Diabetes peripheral neuropathic pain (DPNP) refers to a kind of disease caused by diabetes with neuropathic pain as the main manifestation. After long-term clinical practice and summarization, we put forward that "turbid toxin" is the underlying cause of DPNP, and its influence is present throughout the occurrence and development of diabetes. "Turbid toxin" entering the "collaterals" is found to be the basic pathogenesis of DPNP. In the clinical treatment of the disease, the main method is to remove the turbid toxin, unblock the collaterals and relieve the pain, using the formula of "Turbidity-Removing and Collateral-Unblocking Decoction" , which is adjusted as needed. The application of the treatment method is explained in this paper with actual clinical cases.关键词：diabetes peripheral neuropathic pain;turbid toxin;collaterals;remove turbid toxin and unblock collaterals
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发布时间：2022-10-17 - 摘要：The theory of properties and flavors is one of the basic theories of traditional Chinese medicine. Composing formulas under its guidance is referred to as medicinal combination based on properties and flavors. This study describes the application of Lonicerae and Forsythiae in various prescriptions for syndromes based on the syndrome differentiation system of in wei-qi-ying-blood pattern identification of warm diseases. For wei level patterns, acrid-cool and bitter-sweet medicinals are preferred, and Lonicerae and Forsythiae are used to scatter and dissipate wind-heat. For qi level patterns, the two herbs can clear heat and resolve toxins; warm febrile diseases are treated with acrid-cool and sweet-cold medicinals, and the combined use of acrid-cool medicinals and the approach of transforming yin qi with sweet-bitter medicinals; acrid-cool and slightly bitter medicinals are preferred for warm toxin diseases; and acrid-cool and aromatic medicinals for damp heat diseases. In the treatment of ying level patterns, Lonicerae and Forsythiae eliminate heat in the ying level through the qi level; when pathogenic heat starts to enter the ying level, acrid-cool, sweet-cold, and aromatic medicinals should be considered; as the pathogenic heat grows intense in the ying level, and eventually overwhelms the pericardium, salty-cold and sweet-bitter medicinals should be chosen. Blood level patterns are to be treated with acrid-cool and aromatic medicinals, combined with Lonicerae and Forsythiae which clear heat from collateral channels. The rules for creating prescriptions were analyzed in this study from the perspective of medicinal combination based on properties and flavors, and corresponding clinical records were discovered in Wu Jutong’s Case Records as examples.关键词：Lonicerae;Forsythiae;Wu Jutong;wei-qi-ying-blood;medicinal combination based on properties and flavors
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发布时间：2022-10-17 - 摘要：Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of the nervous system, the etiology and pathogenesis of which remain unclear. Insidious toxins refer to the toxin and evil in the human body, which are often unnoticed and emerge only with the onset of the disease. Its clinical characteristics are strong toxicity, severe illness, or repeated relapse. This paper discusses ALS from the perspective of insidious toxins. It is considered that the characteristics of ALS, such as occult onset, rapid progress, extensive areas of the body affected and typical clinical symptoms, are similar to those of insidious toxins, which include latency, stealthy undermining of the body, ferocious onset and progression, complexity, and variability. It is proposed that congenital, exogenous and endogenous insidious toxins are the cause of ALS. The insidious toxins lurk in the liver, spleen and kidney, damage the brain marrow, block brain collaterals, and take the governor vessels and collateral vessels as the main transmission channels. In treatment, it is proposed as the basic principle to boost essence and fill the marrow, resolve toxins and dredge collaterals. A new perspective for TCM diagnosis and treatment of ALS is provided in this study.关键词：amyotrophic lateral sclerosis;insidious toxin;brain marrow;treatment methods
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发布时间：2022-10-17 - 摘要：Zhang Xichun is a famous doctor in modern China. It can be seen from his book Records of Chinese Medicine with Reference to Western Medicine (yī xué zhōng zhōng cān xī lù ) that he has a profound and unique understanding of the causes and pathogenesis of Bi (impediment) and Wei (flaccidity) diseases. His concurrent treatment of Bi and Wei diseases was elaborate in its development of treatment method and use of drugs. Deficiency of great qi (dà qì) is the pathogenesis basis of Bi diseases and the basic condition of Wei diseases, and original qi is the root of great qi. Qi stagnation and blood stasis is the direct cause of Bi and Wei diseases, and it is closely related to the spleen, liver and kidney. Therefore, Zhang Xichun treated the two types of disease in a simultaneous fashion. He laid emphasis on invigorating original qi and great qi, and regulating stagnation of qi and blood. If qi stagnation and blood stasis is dominant, special attention should be paid to promoting the flow of qi and blood. In addition, Bi and Wei diseases are mostly manifested in the limbs, but also the viscera should be regulated, and different medicinals should be chosen according to the location of the disease. This study summarizes Zhang Xichun’s insights into the etiology and pathogenesis of Bi and Wei diseases and his experience in treatment to guide clinical practices.关键词：Zhang Xichun;Records of Chinese Medicine with Reference to Western Medicine;concurrent treatment of Bi (impediment) and Wei (flaccidity) diseases;academic thoughts
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发布时间：2022-10-17 - 摘要：Bēng Lòu, or metrorrhagia and metrostaxis, refers to the syndrome of serious abnormal menstrual cycle, duration and hypermenorrhea. Li Dongyuan systematically discussed his unique understanding of metrorrhagia and metrostaxis in two articles entitled Three Types of Metrorrhagia and Metrostaxis and Treatments of Metrorrhagia and Metrostaxis in his Medical Encyclopedia of Li Dongyuan. On the basis of his own theory of the spleen and stomach, Li believes that the main pathogenesis of metrorrhagia and metrostaxis is the deficiency and sinking of spleen and stomach qi, combined with exuberance of yin fire, creating damp-heat pathogenic qi. In the clinical syndrome differentiation of metrorrhagia and metrostaxis, Li believes that the most important thing is to determine the cold or heat nature of the disease using the pathological products, and conduct syndrome differentiation based on the typical pulse manifestations. For the treatment, the fundamental method is to tonify the spleen and stomach and purge yin fire, and make adjustments to the formulas according to the syndromes. Patients with spleen and stomach deficiency and heart fire attacking the spleen should be given Menstruation-Regulating, Yang-Rising and Dampness-Removing Decoction; those with kidney yin deficiency and frenetic stirring of ministerial fire should be treated with Blood-Cooling Rehmannia Decoction; in the case of heart qi deficiency and blood deficiency-cold, we should choose Clove, Donkey-Hide Gelatin and Mugwort Decoction; and if the pattern of blood collapse, sinking of qi, and excessive cold-dampness is present, Bupleurum Menstruation-Regulating Decoction, an original formula created by Li, can have desirable efficacy. These are also augmented with the principle of making modifications to the prescription at any time when needed, and the use of moxibustion and emotional counseling. Clarifying these philosophies of Li Dongyuan has guiding significance for the theoretical development and clinical research of metrorrhagia and metrostaxis treatment in later generations.关键词：Li Dongyuan;metrorrhagia and metrostaxis;Yishui School;syndrome differentiation and treatment
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发布时间：2022-10-17 - 摘要：Nipple discharge belongs to the category of rǔ qì (nipple dripping) and rǔ zhī zì chū (spontaneous secretion of milk) in traditional Chinese medicine, while bloody discharge is referred to as rǔ nǜ (thelorrhagia). The Fang’s School of Surgery has rich experience in the diagnosis and treatment of various surgical diseases such as breast diseases. This paper summarizes the experience of the Fang’s School of Surgery in treating nipple discharge from the perspective of the liver and spleen. Syndrome differentiation is the priority in the clinical diagnosis and treatment of the disease. The pathogenesis is believed to lie in the liver and spleen, and it is suggested that nipple discharge is closely related to liver constraint transforming into fire and spleen deficiency causing it to lose control of the blood. In terms of treatment, the method of soothing liver and clearing heat, cooling blood and stanching bleeding is adopted for liver constraint transforming into fire and frenetic flow of the blood caused by blood heat, and in the case of spleen deficiency and the result ant loss of its function to control the blood, phlegm coagulation, and blood stasis, it is needed to invigorate the spleen and promote the flow of qi, invigorate blood and dissolve phlegm. The Fang’s school believes that one herb can have different medical efficacy based on how it is processed, when it is picked, and which part of the plant is used, etc. In the treatment of nipple discharge, Radix Scrophulariae and Herba Agrimoniae are the key ingredients.关键词：syndrome differentiation and treatment from the perspective of the liver and spleen;nipple discharge;Fang’s School of Surgery
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发布时间：2022-10-17 - 摘要：ObjectiveTo analyze the related literature on TCM syndromes of diabetic kidney disease (DKD), and summarize and discuss the distribution characteristics of DKD TCM patterns.MethodsRelevant literatures from January 1, 2016 to January 1, 2021 were retrieved in CNKI, Wanfang Data, VIP, and PubMed, and those that meet the inclusion criteria were screened and a database was created for syndrome extraction, name standardization and separation, and syndrome element extraction.ResultsWe retrieved a total of 1, 498 papers, 109 of the 127 papers included have TCM diagnostic criteria, and a total of 175 patterns were extracted, which were then standardized into 33 TCM patterns. The top five are: qi-yin deficiency, blood stasis, deficiency of both yin and yang, phlegm-turbidity, deficiency of spleen and kidney qi. From the perspective of zang-fu pattern differentiation, kidney accounted for the largest proportion of the 33 types, and deficiency patterns is also considerably common, which are all related to kidney deficiency. We extracted 20 pattern elements related to the nature of the disease and 9 associated with disease locations. The association rule analysis of the 20 property-related elements revealed 6 syndrome element combinations. "Blood stasis-qi deficiency" and "dampness-qi deficiency" , which are the most common ones, have top support, and "dampness-blood stasis" combinations have top confidence and improvement and the second is "qi deficiency-dampness" combinations.ConclusionsThe TCM patterns of DKD were characterized by a mixture of deficiency and excess; deficiency patterns were dominated by qi-yin deficiency, deficiency of both yin and yang, and deficiency of spleen and kidney qi; excessive patterns mainly include blood stasis and phlegm-turbidity; yin deficiency and qi deficiency were the main pathological factors for the disease.关键词：diabetic kidney disease;TCM patterns;pattern elements;literature research
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发布时间：2022-10-17
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