Objective To discuss the characteristics of TCM syndrome factors of large and small artery diseases in acute cerebral infarction.Method According to classification and diagnostic criteria of TOAST and imageology

60 patients with acute cerebral infarction were divided into the group of large artery diseases （n= 27） and the group of small artery diseases （n=33）.The characteristics of TCM syndrome factors in two groups were compared.Result In the group of large artery diseases the occurrence rates of phlegm syndrome

qi deficiency syndrome and blood stasis syndrome were higher significantly than those in the group of small artery diseases （P<0.05）.The comparison in the occurrence rates of wind syndrome

fire-heat syndrome and yin deficiency syndrome between two groups had no significant difference （P>0.05）.The syndrome factors were mainly two-syndrome combination

three-syndrome combination or multi-syndrome combination in the group of large artery diseases

while in the group of small artery diseases mainly two-syndrome combination and single syndrome.The distribution of syndrome factor combination in two groups was different statistically after compared （P<0.05）.Conclusion There are different characteristics in syndrome factors of large and small artery diseases in acute cerebral infarction.