Objective To observe the curative effect of the therapy of replenishing qi

nourishing blood and tonifying kidney on systemic lupus erythematosus （SLE）.Methods The therapy of replenishing qi

nourishing blood and tonifying kidney combined with cyclophosphamide （CTX） impact therapy was used to treat SLE in 30 cases.The curative effect

times of CTX impacts when the patients get obvious effects or effective results

changes of laboratory indexes before and after treatment

hormone minimum maintenance dose

toxic and side effects were observed

and compared with relevant documents both at home and abroad.Results The total effective rate was 90% in 30 cases after the treatment.The times of CTX impacts were different as SLE involved systems were different.In 22 cases the positive antigen of ds-DNA conversed negatively after the treatment

erythrocyte sedimentation rate （ESR） decreased significantly （P<0.01）

levels of complement3 （C3） and complement4 （C4） increased significantly （P<0.05）

and immunoglobulin G （IgG） decreased significantly （P< 0.05）.The hormone minimum maintenance dose was lower and toxic and side effects were less.Conclusion The therapy of replenishing qi

nourishing blood and tonifying kidney combined with CTX impact therapy has good curative effect on SLE.