Objective To discuss the clinical information of pulmonary interstitial fibrosis （PIF）

and compare the relationship between the TCM syndrome manifestations of PIF deficient syndrome and lung CT scores and dimensional scores of SF-36 scale. Methods Clustering method was used in 61 cases of PIF and their clinical information were summed up. The TCM syndrome manifestations of PIF deficient syndrome were compared with lung CT scores and dimensional scores of SF-36 scale by applying rank test. Results The results of both clustering analysis and experiences showed that lung -kidney deficiency and internal blood stasis were the common syndrome manifestations of PIF in clinic. lung CT scores were higher in lung-spleen-kidney deficiency group and lung-kidney deficiency group

and the scores of somatic function were lower in dimensionality of SF-36 scale. Conclusion The common syndrome manifestations of PIF include lung-kidney deficiency and internal blood stasis. The pathological changes of PIF involving kidney deficiency are more serious.