Immunotherapy for malignant tumors is a hot issue in the field of tumor treatment

but its adverse reactions such as immune associated colitis not only affect tumor treatment

but also reduce the life quality of patients.Wumei Pill is of certain clinical effects on immunotherapy related enteritis.The pathogenesis of immunotherapy related colitis is characterized by the deficiency and excess complex

as well as intermingled cold and heat while Wumei Pill can be applied to the disease of intermingled cold and heat.Immunotherapy related colitis belongs to Jueyin diseases while Wumei Pill is the first choice for Jueyin diseases recorded in Treatise on Cold Damage.Visceral cold is the main cause of immunotherapy related colitis

and Wumei Pill is the basic and important prescription indicated for the diarrhea of cold and heat.The whole prescription of Wumei Pill can achieve the therapeutic purpose of tonifying with no pathogenic factors left and clearing away heat without injuring the healthy Qi.Wumei Pill can resist the wind by the sour agents

strengthen Yang with heat herbs

and enrich Yin with herbs of bitter and sour.Moreover

it integrates the methods of warming and clearing

attacking and reinforcing

with remarkable therapeutic effects for immunotherapy related enteritis.Wumei Pill uses sour medicine in great quantity

together with a small amount of cold and heat drugs

to regulate Yin and Yang.Tonic and cathartic are used simultaneously

with care to healthy Qi. Abstract