Objective

2

To analyze the medication regularity of traditional Chinese medicine in the treatment of cerebral palsy

so as to guide clinical medication.

Methods

2

The databases of CNKI

Wanfang medical network

PubMed

Web of science and Cochrane library were searched to screen the clinical research articles on the treatment of cerebral palsy by oral and external use of traditional Chinese medicine. The statistics were made on the frequency of use

efficacy

property

taste and meridian tropism of internal and external use of traditional Chinese medicine

and the cluster analysis and correlation analysis were conducted on high-frequency traditional Chinese medicine.

Results

2

Two hundred and five research articles were included

involving 206 prescriptions. There were two kinds of usage: oral and external. There were 79 formulas for oral administration

and Sijunzi Decoction appeared most frequently. A total of 147 traditional Chinese medicines were included in the statistics

and Danggui (Angelica sinensis)

Huagnqi(Astragalus membranaceus)

Fulin(Poria cocos)

Yizhiren(Fructus Alpiniae Oxyphyllae) and Chuanxiong(Rhizoma Chuanxiong) were used frequently. There were 126 prescriptions for external use

and 108 herbs were included in the statistics. The most frequently used herbs were Shenjincao(Herba Lycopodii)

Tougucao(Herba Vaccinii Urophylli)

Danggui(Angelica sinensis)

Honghua(Flos Carthami) and Niuxi (Radix Achyranthis Bidentatae). The most frequently-used internal herbs were tonifying drugs

accounting for 24.5%

and The most frequently-used external Chinese medicine were wind-and dampness-dispelling drugs

accounting for 21.3%.The most commonly used Chinese herbal medicines for internal and external use were warm in nature

accounting for 42.9% and 46.3% respectively. The drugs with a higher frequency in oral Chinese medicine were sweet

pungent and bitter in taste

while the drugs with a higher frequency in external Chinese medicine were pungent

bitter and sweet. Both the internal and external use of traditional Chinese medicine were mainly for the liver

kidney and spleen meridians. Through correlation analysis and cluster analysis of high-frequency drugs

10 pairs of high-frequency drug combinations can be obtained from high-frequency oral Chinese medicine and 10 pairs of high-frequency drug combinations can be obtained from high-frequency external Chinese medicine. Both high frequency oral and external Chinese medicine can form three clustering formulas.

Conclusions

2

In the treatment of cerebral palsy with traditional Chinese medicine

tonifying deficiency

expelling wind and dampness and relieving exterior syndrome drugs are mainly used for internal use

while dispelling wind-dampness

tonifying deficiency and promoting blood circulation and removing blood stasis drugs are mainly used for external use. The results of high frequency correlation analysis and cluster analysis can provide some reference and guidance for clinical medication.