温阳消水方外敷神阙穴治疗恶性腹腔积液脾肾阳虚证的临床研究

高辰; 宋凤丽; 康宁; 孙颖; 樊树方; 李仝

doi:10.3969/j.issn.2095-6606.2021.04.003

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温阳消水方外敷神阙穴治疗恶性腹腔积液脾肾阳虚证的临床研究

临床研究 | 更新时间：2021-08-23

- 温阳消水方外敷神阙穴治疗恶性腹腔积液脾肾阳虚证的临床研究
- Clinical study of externally applied Wenyang Xiaoshui Formula on the Shenque acupoint for malignant ascites of the spleen-kidney yang-deficiency pattern
- 现代中医临床 2021年28卷第4期页码：12-17
- 作者机构：
  
  1.北京中医药大学第三附属医院　北京　 100029
  2.石家庄市中医院
- 作者简介：
  
  高辰，男，硕士，主治医师
  # 李仝，男，博士，教授、主任医师，博士生导师，E-mail：litong_cool@163.com
- 基金信息：
  
  中央高校基本科研业务费专项资金资助(2018-JYBZZ-JS192)
- DOI：10.3969/j.issn.2095-6606.2021.04.003
  中图分类号： R273
- 纸质出版日期：2021-07-30，
  
  收稿日期：2020-11-10，
- 稿件说明：
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高辰, 宋凤丽, 康宁, 等. 温阳消水方外敷神阙穴治疗恶性腹腔积液脾肾阳虚证的临床研究[J]. 现代中医临床, 2021,28(4):12-17.

Chen Gao, Fengli Song, Ning Kang, et al. Clinical study of externally applied Wenyang Xiaoshui Formula on the Shenque acupoint for malignant ascites of the spleen-kidney yang-deficiency pattern[J]. Modern Chinese Clinical Medicine, 2021,28(4):12-17.
高辰, 宋凤丽, 康宁, 等. 温阳消水方外敷神阙穴治疗恶性腹腔积液脾肾阳虚证的临床研究[J]. 现代中医临床, 2021,28(4):12-17. DOI： 10.3969/j.issn.2095-6606.2021.04.003.

Chen Gao, Fengli Song, Ning Kang, et al. Clinical study of externally applied Wenyang Xiaoshui Formula on the Shenque acupoint for malignant ascites of the spleen-kidney yang-deficiency pattern[J]. Modern Chinese Clinical Medicine, 2021,28(4):12-17. DOI： 10.3969/j.issn.2095-6606.2021.04.003.

摘要

目的

观察温阳消水方外敷神阙穴治疗恶性腹腔积液脾肾阳虚证的临床疗效。

方法

将40例恶性腹腔积液患者随机分为治疗组20例、对照组20例，剔除脱落病例后，治疗组18例、对照组17例。对照组根据患者一般情况进行基础治疗，如营养支持、补充白蛋白、利尿等常规治疗，治疗组在对照组治疗的基础上联合温阳消水方外敷神阙穴治疗。观察腹腔积液最大液深值、平脐腹围值、24 h尿量、临床症状评分、卡氏(KPS)评分、腹腔积液消退疗效，并进行安全性评价。

结果

腹腔积液最大液深值、平脐腹围值治疗组治疗后较本组治疗前均降低(

0.05)，对照组治疗后与本组治疗前比较，差异均无统计学意义(

0.05)，治疗组治疗后较对照组降低明显(

0.05)。24 h尿量治疗组治疗后较本组治疗前增加(

0.05)，对照组治疗后与本组治疗前比较，差异无统计学意义(

0.05)，治疗组治疗后较对照组增加明显(

0.05)。临床症状评分2组治疗后较本组治疗前均降低(

0.05)，治疗组较对照组降低明显(

0.05)。KPS评分治疗组治疗后较本组治疗前升高(

0.05)，对照组治疗后与本组治疗前比较，差异无统计学意义(

0.05)，治疗组治疗后较对照组升高明显(

0.05)。治疗组腹腔积液消退疗效优于对照组(

0.05)。观察2组血常规、肝功能、肾功能检查结果，未见明显不良反应。

结论

温阳消水方外敷神阙穴治疗恶性腹腔积液具有较好的疗效。

Abstract

Objective

To observe the clinical efficacy of externally applied Wenyang Xiaoshui Formula on the Shenque acupoint in patients with malignant ascites of the spleen-kidney yang-deficiency pattern.

Methods

Forty patients with malignant ascites were randomly assigned to the treatment group (

=20) and control group (

=20). With the withdrawal or drop-out excluded

there were 18 cases left in treatment group and 17 in control group. The control group received basic treatment based on the general conditions of the patients

for instance

nutritional support

albumin supplementation

diuretic and other conventional treatments. Apart from the basis of the treatment that control group received

the treatment group received additional externally applied Wenyang Xiaoshui Formula on the Shenque acupoint. The maximum fluid depth in the abdominal cavity

umbilical horizontal abdominal circumference

urine output in 24 hours

clinical symptom score

Karnofsky (KPS) score

efficacy of ascites regression were observed

and its safety was evaluated.

Results

The maximum fluid depth in the abdominal cavity

umbilical horizontal abdominal circumference were significantly decreased after treatment in the treatment group(

0.05)

but there were no significant differences in the control group after treatment(

0.05). There was significant difference between the two groups (

0.05). The urine output in 24 hours were increased after treatment in the treatment group (

0.05)

but there was no significant difference in the control group after treatment(

0.05). The urine output in 24 hours was more significantly increased in the treatment group than in the control group after treatment (

0.05). Clinical symptom scores were significantly decreased after treatment in both groups(

0.05)

more in the treatment group than in the control group after treatment(

0.05). KPS scores were significantly increased in the treatment group after treatment(

0.05)

but not in the control group after treatment(

0.05). KPS scores were more significantly increased in treatment group than in the control group after treatment(

0.05). The efficacy of ascites regression was significantly better in the treatment group than in the control group(

0.05). The blood routine

liver function

and renal function tests in the two groups were observed

with no significant adverse reactions.

Conclusions

The externally applied Wenyang Xiaoshui Formula on the Shenque acupoint is effective in relieving malignant ascites.

关键词

温阳消水方外敷神阙穴恶性腹腔积液中医外治临床研究

Keywords

Wenyang Xiaoshui Formulaexternal applicationShenque acupointmalignant ascitesexternal treatment of TCMclinical research

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