Objective

2

To observe curative effect of the Chinese medical therapy of nourishing yin and downbearing fire for idiopathic central precocious puberty in girls.

Methods

2

Forty-two girls with true idiopathic central precocious puberty were treated with Chinese medical therapy of nourishing yin and downbearing fire.The changes in TCM symptoms

size of the uterus and ovary

gonadotropins

sexhormones

i.e.

luteinizing hormone(LH)

follicle-stimulating hormone (FSH)

estradiol(E2)

X-ray bone age before and after the treatment were recorded.

Results

2

After treatment

the scores of clinical symptoms were significantly decreased

as compared with those before treatment (

P

<

0.05); After treatment

serum LH

FSH and E2 levels were significantly lowered(

P

<

0.05); The size of uterus and ovary was significantly decreased

as compared with those before treatment(

P

<

0.05); After treatment

the bone age/chronological age values were significantly reduced (

P

<

0.05).

Conclusions

2

The Chinese medical therapy of nourishing yin and downbearing fire

which relieves clinical symptoms

is of efficacy for children with idiopathic central precocious puberty.