1.北京中医药大学 北京 100029
2.北京中医药大学东方医院
赵艳芬,女,在读硕士生
# 张永生,男,博士,主任医师,教授、硕士生导师,E-mail:zhyshengcm@163.com
纸质出版日期:2022-05-30,
收稿日期:2021-05-16,
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赵艳芬, 王琦, 姜云宁, 等. 从毒损肺络论治吸烟引起的小气道阻塞[J]. 现代中医临床, 2022,29(3):43-48.
Yanfen ZHAO, Qi WANG, Yunning JIANG, et al. Discussion on treating small airway obstruction caused by smoking from the perspective of injury to pulmonary vessels[J]. Modern Chinese Clinical Medicine, 2022,29(3):43-48.
赵艳芬, 王琦, 姜云宁, 等. 从毒损肺络论治吸烟引起的小气道阻塞[J]. 现代中医临床, 2022,29(3):43-48. DOI: 10.3969/j.issn.2095-6606.2022.03.010.
Yanfen ZHAO, Qi WANG, Yunning JIANG, et al. Discussion on treating small airway obstruction caused by smoking from the perspective of injury to pulmonary vessels[J]. Modern Chinese Clinical Medicine, 2022,29(3):43-48. DOI: 10.3969/j.issn.2095-6606.2022.03.010.
小气道隶属于肺络系统中的气络部分,小气道结构功能的病变影响整个肺络系统以及肺生理功能的正常发挥。小气道阻塞是慢性阻塞性肺疾病的早期阶段,吸烟是其主要的危险因素之一。结合“毒”邪理论和络病学说,认为烟草烟雾是本病的使动因素,烟雾对小气道的影响包括介导气道炎症反应、黏液分泌和气道阻塞以及肺内组织损伤。烟毒伤络过程包括:留滞气络积蕴成毒阶段、成毒络损阶段和络损内生新毒阶段。治疗强调排毒通络、益气养阴,初期留滞气络积蕴成毒阶段宜清肺润络排毒,烟雾积聚成毒络损阶段宜益气通络排毒,络损内生新毒阶段宜逐瘀化痰通络。
Small airways belong to the qi collateral of the lung collaterals
and their damages may result in abnormalities of the entire lung collateral system
and its physiological functions. Small airways obstruction is the early stage of chronic obstructive pulmonary disease (COPD)
for which smoking has been recognized as one of the main risk factors. Based on a combination of the theory of "toxic" pathogen and of pulmonary collateral diseases
this study proposes that tobacco smoke is the driving factor of this disease. The injury of lung collaterals by tobacco smoke is manifested in its effect on small airways
which mediates airway inflammation
mucus secretion and eventual obstruction of the passages. Tissue damage in the lungs are caused by smoke invading qi collaterals
which mainly involves the stages smoke evil accumulating in the qi collaterals until toxic levels
the smoke toxins inducing collateral damage
and new toxins result ing from the damaged collaterals. For the treatment
the focus should be placed on removing the toxins and unblocking the collaterals
tonifying qi and nourishing yin. At the initial stage
it is advisable to clear the lungs
moisten collaterals and expel the toxins. At the second stage
the key is to nourish qi and unblock the collaterals and remove the toxins. To deal with the new toxins generated in the third stage
it is suggested to remove stasis
dissolve phlegm and unblock the collaterals.
慢性阻塞性肺疾病小气道阻塞吸烟毒损肺络毒邪理论络病学说
chronic obstructive pulmonary diseasesmall airway obstructionsmokingtoxic damage to lungsthe theory of "toxin"the theory of collateral disease
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