1.河北中医学院 石家庄 050011
2.河北中医学院第一附属医院
朱浩维,在读硕士生
#戎士玲,教授,主任医师、硕士生导师,E-mail:hbrong111@sina.com
纸质出版日期:2022-09-30,
收稿日期:2021-05-26,
移动端阅览
朱浩维, 戎士玲, 李佃贵, 等. 从“浊毒”入“络”论治糖尿病周围神经痛[J]. 现代中医临床, 2022,29(5):48-51.
ZHU Haowei, RONG Shiling, LI Diangui, et al. Treatment of diabetic peripheral neuropathic pain from the perspective of "turbid toxin" entering "collaterals"[J]. Modern Chinese Clinical Medicine, 2022,29(5):48-51.
朱浩维, 戎士玲, 李佃贵, 等. 从“浊毒”入“络”论治糖尿病周围神经痛[J]. 现代中医临床, 2022,29(5):48-51. DOI: 10.3969/j.issn.2095-6606.2022.05.011.
ZHU Haowei, RONG Shiling, LI Diangui, et al. Treatment of diabetic peripheral neuropathic pain from the perspective of "turbid toxin" entering "collaterals"[J]. Modern Chinese Clinical Medicine, 2022,29(5):48-51. DOI: 10.3969/j.issn.2095-6606.2022.05.011.
糖尿病周围神经痛(DPNP)是指由糖尿病导致的以神经病理性疼痛为主要表现的一类疾病。笔者经过长期临床实践与总结,提出“浊毒”是DPNP的基本病因,其影响贯穿糖尿病发生发展的始终。“浊毒”入“络”是DPNP的基本病机。临床治疗DPNP时,以化浊解毒、通络止痛为大法,并拟“化浊通络汤”方加减。结合临床病案,对“化浊通络”法在DPNP中的应用进行介绍。
Diabetes peripheral neuropathic pain (DPNP) refers to a kind of disease caused by diabetes with neuropathic pain as the main manifestation. After long-term clinical practice and summarization
we put forward that "turbid toxin" is the underlying cause of DPNP
and its influence is present throughout the occurrence and development of diabetes. "Turbid toxin" entering the "collaterals" is found to be the basic pathogenesis of DPNP. In the clinical treatment of the disease
the main method is to remove the turbid toxin
unblock the collaterals and relieve the pain
using the formula of "Turbidity-Removing and Collateral-Unblocking Decoction"
which is adjusted as needed. The application of the treatment method is explained in this paper with actual clinical cases.
糖尿病周围神经痛浊毒络脉化浊通络
diabetes peripheral neuropathic painturbid toxincollateralsremove turbid toxin and unblock collaterals
中国医师协会神经内科医师分会疼痛和感觉障碍专委会.糖尿病性周围神经病理性疼痛诊疗专家共识[J].全科医学临床与教育,2019, 17(2): 100-103, 107.
YU M,FANG P H,WANG H,et al.Beneficial effects of galanin system on diabetic peripheral neuropathic pain and its complications[J/OL].Peptides,2020,134:170404[2021-03-04].https://doi.org/10.1016/j.peptides.2020.170404https://doi.org/10.1016/j.peptides.2020.170404.
袁晨曦,陈欣悦,吴颖,等.糖尿病周围神经病变患者生活质量评估量表的研究进展[J].中国护理管理,2019, 19(8): 1252-1255.
李佃贵.中医浊毒论[M].北京:人民卫生出版社,2016: 17.
裴林,李佃贵,等.浊毒浅识[J].河北中医,2010, 32(1): 24-25.
庞国明,闫镛,朱璞,等.糖尿病周围神经病变中医诊疗规范初稿[J].中华中医药杂志,2010, 25(2): 260-264.
中华中医药学会糖尿病分会.糖尿病周围神经病变中医临床诊疗指南(2016年版)[J].中医杂志,2017, 58(7): 625-630.
中华中医药学会.糖尿病中医防治指南[J].中国中医药现代远程教育,2011, 9(4): 148-151.
庞国明,闫镛,郑晓东.糖尿病周围神经病变中医防治指南[J].中国中医药现代远程教育,2011, 9(22): 119-121.
徐伟超,李佃贵,刘建平,等.浊毒理论创新中医病因病机学[J].中国中西医结合杂志,2019, 39(8): 913-915.
赵乃倩,余叶蓉,谭惠文,等.糖脂联合毒性导致胰岛β细胞功能障碍[J].中华内分泌代谢杂志,2009, 25(1): 28-29.
冯英和,李国素,谢子琪.浅论浊毒与糖耐量异常[J].现代中西医结合杂志,2012, 21(5): 521-522.
喻昌.医门法律[M].史欣德,整理.北京:人民卫生出版社,2006: 8.
叶天士.临证指南医案[M].苏礼,整理.北京:人民卫生出版社,2006: 6.
马运涛,吴深涛.吴深涛辨治痛性糖尿病周围神经病变经验[J].上海中医药杂志,2019, 53(8): 2-4.
金鑫,李小娟.络病与糖尿病周围神经病变[J].实用中医内科杂志,2016, 30(6): 35-37.
郭建仪,吕静,马铭悦,等.基于网络药理学及分子对接探讨“藿香-佩兰-大黄”角药治疗慢性肾衰竭的作用机制[J].湖北民族大学学报(医学版),2021, 38(3): 29-34.
徐婧,刘喜明,马文欣,等.基于网络药理学探讨“白术-茯苓”配伍治疗代谢综合征的作用机制[J].中医学报,2022, 37(1): 165-172.
刘珊珊,郭杰,李宗艾,等.泽泻化学成分及药理作用研究进展[J].中国中药杂志,2020, 45(7): 1578-1595.
李时珍.本草纲目[M].北京:线装书局,2019: 6.
邹妍,鄢海燕.中药木瓜的化学成分和药理活性研究进展[J].国际药学研究杂志,2019, 46(7): 507-515.
张静,杨义芳,吴春珍,等.当归-川芎药对超临界提取物配伍红花抗心肌缺血的谱效关系研究[J].中草药,2013, 44(14): 1944-1950.
曹晔文,肖瑶,许涛,等.基于网络药理学的“桑枝-桂枝”药对治疗类风湿关节炎的作用机制研究[J].海南医学院学报,2021, 27(8): 592-602.
王志江,梁丽丽,等.草本威灵仙的抗炎镇痛和止血作用[J].医药导报,2017, 36(5): 489-492.
张立新,岳丹丹,等.透骨草化学成分的分离鉴定及生物活性研究[J].中国药物化学杂志,2020, 30(10): 606-612.
中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020年版)[J].中华内分泌代谢杂志,2021, 37(4): 311-398.
PAOANAS N,ZIEGLER D.Emerging drugs for diabetic peripheral neuropathy and neuropathic pain[J].Expert Opinion on Emerging Drugs,2016, 21(4): 393-407.
SUZANNE A N,RITU S,JULIE M W,et al. Non-pharmacologic treatments for symptoms of diabetic peripheral neuropathy:a systematic review[J].Current Medical Research and Opinion,2019, 35(1): 15-25.
王淑珍.糖尿病周围神经病变的治疗进展[J].医学理论与实践,2017, 30(9): 1281-1284.
杨丽,高怀林.从“络”论治糖尿病周围神经病变研究进展[J].疑难病杂志,2022, 21(4): 428-431.
0
浏览量
50
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构