调泌针法治疗多囊卵巢综合征排卵障碍的临床研究

张小雪; 郭新峰; 王翰林; 谢长才

doi:10.3969/j.issn.2095-6606.2022.06.003

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调泌针法治疗多囊卵巢综合征排卵障碍的临床研究

临床研究 | 更新时间：2022-12-03

- 调泌针法治疗多囊卵巢综合征排卵障碍的临床研究
- Clinical research of treating ovulation disorders in polycystic ovary syndrome with endocrine-regulating acupuncture
- 现代中医临床 2022年29卷第6期页码：11-16
- 作者机构：
  
  1.广州中医药大学第二临床医学院　广州　510405
  2.广东省中医院
- 作者简介：
  
  张小雪，女，硕士，住院医师
  #谢长才，男，博士，主任医师，硕士生导师，E-mail：hxie114@163.com
- 基金信息：
  
  广东省自然科学基金面上项目(2019A1515011504);省部共建中医湿证国家重点实验室专项(SZ2021ZZ08)
- DOI：10.3969/j.issn.2095-6606.2022.06.003
  中图分类号： R246.3
- 纸质出版日期：2022-11-30，
  
  收稿日期：2022-04-10，
- 稿件说明：
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张小雪, 郭新峰, 王翰林, 等. 调泌针法治疗多囊卵巢综合征排卵障碍的临床研究[J]. 现代中医临床, 2022,29(6):11-16.

ZHANG Xiaoxue, GUO Xinfeng, WANG Hanlin, et al. Clinical research of treating ovulation disorders in polycystic ovary syndrome with endocrine-regulating acupuncture[J]. Modern Chinese Clinical Medicine, 2022,29(6):11-16.
张小雪, 郭新峰, 王翰林, 等. 调泌针法治疗多囊卵巢综合征排卵障碍的临床研究[J]. 现代中医临床, 2022,29(6):11-16. DOI： 10.3969/j.issn.2095-6606.2022.06.003.

ZHANG Xiaoxue, GUO Xinfeng, WANG Hanlin, et al. Clinical research of treating ovulation disorders in polycystic ovary syndrome with endocrine-regulating acupuncture[J]. Modern Chinese Clinical Medicine, 2022,29(6):11-16. DOI： 10.3969/j.issn.2095-6606.2022.06.003.

摘要

目的

观察调泌针法治疗多囊卵巢综合征排卵障碍的疗效和安全性。

方法

自2020年6月—2021年2月，收集在广东省中医院针灸及妇科门诊就诊并符合纳入排除标准的患者65例，采用简单随机化方法，按照先后顺序随机分为对照组(克罗米芬组33例)和治疗组(调泌针法组32例)。2组均在生活方式指导的基础上进行，对照组予口服枸橼酸氯米芬片，从月经第2～5日开始服用，50 mg/d，共5 d；治疗组予调泌针法针刺，隔日1次，每周3次，2组各治疗3个月经周期，观察2组的性激素水平、中医症状评分的变化，排卵及妊娠情况并对比其差异。

结果

①排卵率：治疗组排卵率为60.87%；对照组为63.24%；经统计学分析差异没有统计学意义(

0.05)。②性激素水平：治疗后2组卵泡刺激素(Follicle-stimulating hormone，FSH)较治疗前明显增高，黄体生成素(Luteinizing hormone，LH)、LH/FSH、睾酮(Testosterone，T)较治疗前均有明显降低，差异具有统计学意义(

0.05)。治疗组LH、LH/FSH、T降低幅度更大，差异有统计学意义(

0.05)；2组在FSH增高方面无明显差异(

0.05)。③妊娠率：治疗组妊娠率42.86%；对照组妊娠率41.94%，经比较，2组无明显差异(

0.05)。

结论

调泌针法可改善多囊卵巢综合征排卵障碍，有助于促进排卵和生育，改善性激素水平。

Abstract

Objective

To observe the efficacy and safety of endocrine-regulating acupuncture in the treatment of ovulation disorders in polycystic ovary syndrome.

Methods

From June 2020 to February 2021

65 patients were recruited who met the inclusion criteria in the Acupuncture Clinics and Gynecological Clinics of Guangdong Provincial Hospital of Chinese Medicine. The simple randomization method was used and they were randomly divided into two groups according to the order of their inclusion

namely the control group (clomiphene group

33 cases) and the treatment group (endocrine-regulating acupuncture group

32 cases). Both groups were given lifestyle guidance. The control group was given clomiphene citrate tablets

starting from the 2nd to 5th day of menstruation

50 mg/d

for 5 days; the treatment group was given endocrine-regulating acupuncture

once every other day

three times a week. The two groups were treated for 3 menstrual cycles

and the changes in sex hormone levels

TCM symptom scores

ovulation and pregnancy were observed and the differences were identified.

Results

① Ovulation rate: The ovulation rate of the treatment group was 60.87%; the control group was 63.24%; the difference was not significant after statistical analysis (

0.05). ② Sex hormone level: after treatment

follicle-stimulating hormone (FSH) in the two groups was significantly higher than before treatment; luteinizing hormone (LH)

LH/FSH

testosterone (T) were significantly lower than before treatment

with statistical significance (

0.05).The reduction of LH

LH/FSH and T in the treatment group was greater

and the difference was significant (

0.05); in terms of FSH increase

the difference between the two groups was not statistically significant (

0.05). ③ Pregnancy rate: The pregnancy rate of the treatment group was 42.86%; the pregnancy rate of the control group was 41.94%. After comparison

there was no significant difference between the two groups (

0.05).

Conclusion

Endocrine-regulating acupuncture can improve ovulation disorders in polycystic ovary syndrome

help promote ovulation and fertility

and improve sex hormone levels.

关键词

调泌针法多囊卵巢综合征排卵障碍

Keywords

endocrine-regulating acupuncturepolycystic ovary syndromeovulation disorders

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