从“肾藏志”理论探讨阿尔茨海默病的治疗思路

郑茂凤; 时晶; 倪敬年; 魏明清; 田金洲

doi:10.3969/j.issn.2095-6606.2023.01.015

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从“肾藏志”理论探讨阿尔茨海默病的治疗思路

思路与方法 | 更新时间：2023-02-02

- 从“肾藏志”理论探讨阿尔茨海默病的治疗思路
- Discussion on the treatment of Alzheimer disease from the theory of "the kidney stores the will"
- 现代中医临床 2023年30卷第1期页码：65-68
- 作者机构：
  
  北京中医药大学东直门医院　北京　100700
- 作者简介：
  
  郑茂凤，女，在读硕士生
  #田金洲，男，教授、主任医师，博士生导师，E-mail：jztian@hotmail.com
- 基金信息：
  
  国家重点研发计划项目资助课题(2018YFC1704101)
- DOI：10.3969/j.issn.2095-6606.2023.01.015
  中图分类号： R259
- 纸质出版日期：2023-01-30，
  
  收稿日期：2022-03-30，
- 稿件说明：
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郑茂凤, 时晶, 倪敬年, 等. 从“肾藏志”理论探讨阿尔茨海默病的治疗思路[J]. 现代中医临床, 2023,30(1):65-68.

ZHENG Maofeng, SHI Jing, NI Jingnian, et al. Discussion on the treatment of Alzheimer disease from the theory of "the kidney stores the will"[J]. Modern Chinese Clinical Medicine, 2023,30(1):65-68.
郑茂凤, 时晶, 倪敬年, 等. 从“肾藏志”理论探讨阿尔茨海默病的治疗思路[J]. 现代中医临床, 2023,30(1):65-68. DOI： 10.3969/j.issn.2095-6606.2023.01.015.

ZHENG Maofeng, SHI Jing, NI Jingnian, et al. Discussion on the treatment of Alzheimer disease from the theory of "the kidney stores the will"[J]. Modern Chinese Clinical Medicine, 2023,30(1):65-68. DOI： 10.3969/j.issn.2095-6606.2023.01.015.

摘要

阿尔茨海默病(AD)是一种以进行性认知损害为特征的神经变性病，也是最常见的痴呆类型。AD进展期间有多个证候演变并具有一定规律性，基于《黄帝内经》“肾藏志”理论，提出肾虚证候级联假说。从“肾藏志”理论探讨AD的治疗思路，“肾藏志”功能正常，则人的记忆和神志活动保持正常。“肾藏志”异常不仅是AD的启动因子，也是贯穿AD全过程的核心病机。“肾藏志”与记忆和人体的精神活动均有密切联系。补肾生精强志是AD的基本治法，早期以补肾为主，中期以活血、化痰、泻火为主，晚期以解毒固脱为主，为序贯疗法中“早期补肾为主并贯穿全程”提供了理论依据。

Abstract

Alzheimer’s disease (AD)

a neurodegenerative disease characterized by progressive cognitive impairment

is the most common type of dementia. During the progression of AD

multiple TCM patterns may be present

which follow certain rules. Based on the theory of "the kidney stores the will" proposed in

The Yellow Emperor’s Inner Classic

hypothesis of kidney deficiency in AD and its sequential therapy based on kidney-reinforcing was proposed in this study. The therapeutic idea of AD is discussed from the theory of "the kidney stores the will" . If this function is normal

the memory and mental activity remain normal. Abnormalities in the will-storing function of the kidney are not only the initiator of AD

but also the core pathogenesis throughout the whole process of the disease. In light of the close connection between "the kidney stores the will" and the memory and the spiritual activities of human body

the method of supplementing the kidney

producing essence and strengthening the will is proposed as the basic treatment of AD. The focus should be placed on supplementing the kidney in the early stage

invigorating blood

resolving phlegm and draining fire in the middle

and resolving toxins and stopping collapse in the late stage

which provides a theoretical basis for "supplementing the kidney in the early stage and throughout the treatment" in the sequential therapy.

关键词

阿尔茨海默病肾虚级联假说肾藏志

Keywords

Alzheimer diseasecascade hypothesis of kidney deficiencythe kidney stores the will

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