1.浙江中医药大学第三临床医学院 杭州 310053
2.浙江中医药大学附属宁波中医院
徐新宇,男,在读硕士生
# 崔云,男,硕士,主任医师,博士生导师,E-mail:nbszyy@sina.com
纸质出版日期:2023-05-30,
收稿日期:2022-06-28,
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徐新宇, 张婷, 叶有骏, 等. 基于肠道菌群探讨从脾胃论治慢性前列腺炎[J]. 现代中医临床, 2023,30(3):51-55. DOI: 10.3969/j.issn.2095-6606.2023.03.010.
XU Xinyu, ZHANG Ting, YE Youjun, et al. To explore the treatment of chronic prostatitis from spleen and stomach based on gut microbiota[J]. Modern Chinese Clinical Medicine, 2023,30(3):51-55. DOI: 10.3969/j.issn.2095-6606.2023.03.010.
慢性前列腺炎是男科常见疾病,由于其病因不明、症状复杂、病程迁延,增加了临床治疗难度。目前,立足脾胃后天之本濡养诸脏腑的生理特点,从脾胃虚衰角度来解释本病病因病机和指导治疗成为临床研究的新方向。随着肠道菌群的研究不断深入,肠道菌群与脾胃和慢性前列腺炎的关系被逐渐揭开,如肠道菌群在生理功能、致病因素、症状表现、病理状态以及药物调节方面与脾胃相似,慢性前列腺炎在病名症状、病因病机、治法方药上均与脾虚密切相关,且肠道菌群可借助神经、内分泌、免疫调节来诱发慢性前列腺炎。基于三者的相互联系,故认为脾虚导致肠道菌群失调进而诱发慢性前列腺炎,这不仅有益于解释慢性前列腺炎的发病机制,更可作为慢性前列腺炎从脾胃论治的科学支撑。
Chronic prostatitis (CP) is a common disease in urology and andrology
which is a tricky disease due to its unknown etiology
complicated symptoms and prolonged course. At present
it has become a new direction of clinical research to explain the etiology
pathogenesis and treatment of this disease from the perspective of deficiency of the spleen and stomach based on the physiological characteristics of the two as the foundation of acquired constitution to nourish all viscera. With the research advancing
the relationship between gut microbiota and the spleen and stomach and CP has been gradually uncovered. For example
gut microbiota is similar to the spleen and stomach in physiological function
pathogenic factors
symptom manifestations
pathological state and medication regulation. CP is closely related to spleen deficiency in terms of disease name
symptoms
pathogenesis
treatment and prescriptions. Moreover
gut microbiota can induce CP through nerve
endocrine and immune regulation. Based on the relationship between the three
we believe that spleen deficiency leads to gut microbiota imbalance and thus induces CP
which can not help explain its pathogenesis
but also be used as scientific support for treating the disease from the perspective of the spleen and stomach.
慢性前列腺炎肠道菌群脾胃益生菌植物多糖病因学
chronic prostatitisgut microbiotaspleen and stomachprobioticsplant polysaccharideetiology
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