基于“脾主运化”探讨肠道—卵巢轴与多囊卵巢综合征的相关性
Exploring the relevance of the intestinal-ovarian axis to polycystic ovary syndrome based on the principle that the spleen governs transportation and transformation
- 现代中医临床 2023年30卷第5期 页码：89-93
- 作者机构：
1.广州中医药大学 广州 510405
2.广州中医药大学第一附属医院
- 作者简介：
曾根平，在读硕士生
# 曾蕾，女，博士，副主任医师，硕士生导师
- 基金信息：国家自然科学基金资助项目(81804135);罗颂平全国名老中医药专家传承工作室(国中医药人教函【2022】75号);罗颂平全国名中医传承工作室(国中医药人教函【2022】5号);深圳市“医疗卫生三名工程”项目资助(SZZYSM202106003);2023年中国中西医结合妇产科专项研究基金滋肾育胎丸专项(FCK-ZSYTW－09);国家中医药传承创新中心科研专项“青年项目”(2022QN21)
DOI：10.3969/j.issn.2095-6606.2023.05.018
中图分类号： R271.9纸质出版日期：2023-09-30，
收稿日期：2023-01-18，
- 稿件说明：
移动端阅览
曾根平, 缪雨希, 黎佩银, 等. 基于“脾主运化”探讨肠道—卵巢轴与多囊卵巢综合征的相关性[J]. 现代中医临床, 2023,30(5):89-93.
ZENG Genping, MIAO Yuxi, LI Peiyin, et al. Exploring the relevance of the intestinal-ovarian axis to polycystic ovary syndrome based on the principle that the spleen governs transportation and transformation[J]. Modern Chinese Clinical Medicine, 2023,30(5):89-93.
曾根平, 缪雨希, 黎佩银, 等. 基于“脾主运化”探讨肠道—卵巢轴与多囊卵巢综合征的相关性[J]. 现代中医临床, 2023,30(5):89-93. DOI： 10.3969/j.issn.2095-6606.2023.05.018.
ZENG Genping, MIAO Yuxi, LI Peiyin, et al. Exploring the relevance of the intestinal-ovarian axis to polycystic ovary syndrome based on the principle that the spleen governs transportation and transformation[J]. Modern Chinese Clinical Medicine, 2023,30(5):89-93. DOI： 10.3969/j.issn.2095-6606.2023.05.018.
摘要
多囊卵巢综合征(polycystic ovary syndrome，PCOS)是育龄期女性常见神经内分泌代谢性疾病。越来越多研究表明，肠道菌群与PCOS之间存在密切联系。菌群失调参与PCOS发生发展，影响机体内分泌、炎症及能量代谢，调节肠道菌群可有效改善PCOS症状。祖国医学的“脾胃”包含肠道菌群，“脾主运化”的科学内涵包括肠道菌群及其互相牵制影响的内在联系。中医学认为PCOS关键病机当属脾虚痰湿内蕴，法当健脾胃、益生化、行气血、化痰湿，这与调节肠道菌群机理不谋而合。故本文立足于“脾主运化”，剖析肠道—卵巢轴与PCOS的相关性，旨在揭示肠道—卵巢轴及“脾主运化”在PCOS诊治中的重要性。
Abstract
Polycystic ovary syndrome (PCOS) is a common neuroendocrine metabolic disorder in women of childbearing age. A growing body of research has shown a strong link between intestinal flora and PCOS. Dysbiosis is involved in the development of PCOS and affects the endocrine
inflammatory and energy metabolism of the body
and regulating the intestinal flora can effectively improve the symptoms of PCOS. The scientific connotation of "the spleen and stomach" in TCM theories includes the intestinal flora
and the concept that "the spleen is responsible for transport and transformation" essentially involves the intestinal flora and its interlocking influence. TCM believes that the key pathogenesis of PCOS is spleen deficiency
and the result ant accumulation of phlegm and dampness
and the focus of treatment should be placed on strengthening the spleen and stomach
aid generation and transformation
promote the movement qi and blood
and resolve phlegm and dampness
which coincides with the mechanism of regulating the intestinal flora. Therefore
based on the principle of "the spleen governs transportation and transformation"
this article analyses the relevance of the intestinal-ovarian axis to PCOS
aiming to reveal the importance of the intestinal-ovarian axis and the theory of "generation and transformation" in the diagnosis and management of PCOS.
关键词
多囊卵巢综合征脾主运化肠道菌群肠道—卵巢轴
Keywords
PCOSgeneration and transformationintestinal florathe intestinal-ovarian axis.
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